|Cat. No. 359 002||200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.|
WB: 1 : 1000 (AP staining) gallery
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
|Immunogen||Recombinant protein corresponding to AA 1 to 187 from mouse CAML (UniProt Id: P49070)|
Reacts with: rat (Q6DGG9), mouse (P49070).
Other species not tested yet.
|Specificity||Specific for CAML.|
The integral membrane protein CAML (Calcium signal-modulating cyclophilin ligand) is highly conserved throughout species and constitutively expressed in immune cells and various cells of the nervous system. Besides its link to calcium signaling, it has recently been shown that CAML reconstitutes together with WRB the TRC40 receptor at the endoplasmic reticulum, which mediates post-translationally insertion of tail-anchored membrane proteins into the ER.