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CNP 1 - 355 006

A marker for oligodendrocytes
Polyclonal chicken purified antibody
Cat. No.: 355 006
Amount: 50 µg
Price: 370.00 €
Cat. No. 355 006 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Ovalbumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 AP staining gallery  
ICC: 1 : 1000 (see remarks) gallery  
IHC: 1 : 500 (see remarks) gallery  
IHC-P/FFPE: 1 : 4000 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 420 from mouse CNP1 (UniProt Id: P16330)
Reactivity Reacts with: rat (P13233), mouse (P16330).
Other species not tested yet.
Specificity Specific for CNP 1.
Remarks

ICC: Methanol fixation is recommended.

IHC: Antigen retrieval (10mM citrate, pH 6.0, overnight at 60°C) is recommended.

Data sheet 355_006.pdf
Cat. No.: 355 006
Quantity: 50 µg
Price: 370.00 €
Background
The 2', 3'-cyclic nucleotide 3'-phosphodiesterase CNP 1, also referred to as CNPase and CNP, is one of the most abundant membrane-associated enzymes in the myelin sheath of the vertebrate nervous system.
It is assumed that CNP 1 participates in RNA metabolism of myelinating oligodendrocytes.