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Home > Products > 355 002

CNP1 antibody - 355 002 K.O.

CNP1 is a marker for oligodendrocytes
Rabbit polyclonal antiserum
Cat. No.: 355 002
Amount: 200 µl
Price: $355.00
Cat. No. 355 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen Recombinant protein corresponding to AA 1 to 420 from mouse CNP1 (UniProt Id: P16330)
Reactivity Reacts with: rat (P13233), mouse (P16330).
Other species not tested yet.
Specificity K.O. validated
Data sheet 355_002.pdf

References for CNP1 - 355 002

Rab6A as a Pan-Astrocytic Marker in Mouse and Human Brain, and Comparison with Other Glial Markers (GFAP, GS, Aldh1L1, SOX9).
Melzer L, Freiman TM, Derouiche A
Cells (2021) 101: . 355 002 IHC; tested species: mouse
Immunohistochemical analysis of spinal cord components in mouse model of experimental autoimmune encephalomyelitis.
Pyka-Fosciak G, Stasiolek M, Litwin JA
Folia histochemica et cytobiologica (2018) 563: 151-158. 355 002 IHC; tested species: mouse
Cat. No.: 355 002
Amount: 200 µl
Price: $355.00
Rab6A as a Pan-Astrocytic Marker in Mouse and Human Brain, and Comparison with Other Glial Markers (GFAP, GS, Aldh1L1, SOX9).
Melzer L, Freiman TM, Derouiche A
Cells (2021) 101: . 355 002 IHC; tested species: mouse
Immunohistochemical analysis of spinal cord components in mouse model of experimental autoimmune encephalomyelitis.
Pyka-Fosciak G, Stasiolek M, Litwin JA
Folia histochemica et cytobiologica (2018) 563: 151-158. 355 002 IHC; tested species: mouse
WB
ICC
IHC
IHC-P
Background
The 2', 3'-cyclic nucleotide 3'-phosphodiesterase CNP 1, also referred to as CNPase and CNP, is one of the most abundant membrane-associated enzymes in the myelin sheath of the vertebrate nervous system.
It is assumed that CNP 1 participates in RNA metabolism of myelinating oligodendrocytes.
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