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SOX 2 - 347 003

Transcription factors involved in CNS development
Polyclonal rabbit purified antibody
Cat. No.: 347 003
Amount: 50 µg
Price: $370.00
Cat. No. 347 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 200 gallery  
Immunogen Synthetic peptide corresponding to AA 303 to 319 from mouse SOX2 (UniProt Id: P48432)
Reactivity Reacts with: rat, mouse (P48432), human (P48431).
Other species not tested yet.
Specificity Specific for SOX 2.
Data sheet 347_003.pdf

References for SOX 2 - 347 003

Loss of FEZ1, a gene deleted in Jacobsen syndrome, causes locomotion defects and early mortality by impairing motor neuron development.
Gunaseelan S, Wang Z, Tong VKJ, Ming SWS, Razar RBBA, Srimasorn S, Ong WY, Lim KL, Chua JJE
Human molecular genetics (2021) : . 347 003 ICC; tested species: human
Cat. No.: 347 003
Quantity: 50 µg
Price: $370.00
Loss of FEZ1, a gene deleted in Jacobsen syndrome, causes locomotion defects and early mortality by impairing motor neuron development.
Gunaseelan S, Wang Z, Tong VKJ, Ming SWS, Razar RBBA, Srimasorn S, Ong WY, Lim KL, Chua JJE
Human molecular genetics (2021) : . 347 003 ICC; tested species: human
Background
Sex determining region of Y chromosome (Sry)-related high mobility group box1-3) or SOX 1-3 proteins belong to the earliest transcription factors expressed in the developing CNS
Sox 1, Sox 2 and Sox 3 constitute the B1-subgroup of the Sox gene family 12. They are expressed by most progenitor cells of the developing CNS and are generally downregulated by neural cells when they exit the cell cycle and differentiate.