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c-Myc antibody - 343 011C2

c-Myc is a protein involved in the control of cell proliferation
Mouse monoclonal purified IgG
Cat. No.: 343 011C2
Amount: 100 µg
Price: $465.00
Cat. No. 343 011C2 100 µg purified IgG, lyophilized, fluorescence-labeled with Cyanine 2.

Fluorescence labeled antibodies conjugated to (Sulfo-)Cyanine dyes are well suited for standard epi-fluorescence setups and confocal microscopy.

Cyanine 2: λex 492 nm / λem 508 nm
Sulfo-Cyanine 3: λex 554 nm / λem 568 nm
Sulfo-Cyanine 5: λex 649 nm / λem 667 nm

(Sulfo-)Cyanine 5 dyes are well suited for STORM high resolution microscopy.
Sulfo-Cyanines are highly water soluble and allow a higher labeling degree and consequently brighter conjugates.

Albumin was added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Either add 1:1 (v/v) glycerol, then aliquot and store at -20°C until use, or store aliquots at -80°C without additives.
Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye.
Applications
 
WB: N/A
IP: N/A
ICC: 1 : 500 gallery  
IHC: yes
IHC-P: yes
Label Cyanine 2
Clone 9E10
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to AA 408 to 432 from human c-Myc (UniProt Id: P01106)
Epitop AA 410 to 419 from human c-Myc (UniProt Id: P01106)
Reactivity Reacts with: human (P01106).
Other species not tested yet.
Data sheet 343_011c2.pdf
Cat. No.: 343 011C2
Amount: 100 µg
Price: $465.00
Background
The c-Myc oncogene (p62 c-Myc) is a nuclear protein that is involved in the control of normal cellular proliferation and differentiation. Deregulated expression of c-Myc induces apoptosis in different cell types.
The C-terminal c-Myc amino acids are widely used in combination with eukaryotic expression vectors encoding proteins with c-Myc epitope tag.