CRMP1 antibody - 336 003

CRMP1 is a phospho-proteins involved in neuronal development

Rabbit polyclonal purified antibody

Cat. No.: 336 003

Amount: 50 µg

Price: $375.00

Cat. No. 336 003	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 (AP staining) gallery IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section. Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section. Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section. Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section. Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen	Synthetic peptide corresponding to AA 441 to 455 from human CRMP1 (UniProt Id: Q14194)
Reactivity	Reacts with: human (Q14194), rat (Q62950), mouse (P97427). Other species not tested yet.
Specificity	Specific for CRMP 1 (isoform 1) and LCRMP 1 (isoform 2).
Data sheet	336_003.pdf

Cat. No.: 336 003

Amount: 50 µg

Price: $375.00

Background

Collapsing response mediator proteins (CRMPs) are a family of five intracellular phospho-proteins implicated in signal transduction of neurite outgrowth and axonal guidance. They are differentially expressed during neuronal development.
CRMP 1, also known as DPYSL 1, DRP 1 and ULIP 3,and CRMP 2 have been shown to interact with tubulin dimers promoting microtubule assembly for neurite elongation.

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