Cat. No.: 329 002
Amount: 200 µl
Price:
$355.00
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| Cat. No. 329 002 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not recommended IHC-P: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 1 to 26 from mouse ABP1 (UniProt Id: Q62418) |
| Reactivity |
Reacts with: rat (Q9JHL4), mouse (Q62418). Other species not tested yet. |
| Specificity | Specific for ABP1. |
| Data sheet | 329_002.pdf |
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The Actin-binding protein 1 (ABP1) also known as SH3P7, Dbnl or Debrin-like protein binds to actin filaments especially at sites that represent cellular growth.
In neurons ABP1 has been shown to interact with the scaffoliding PSD proteins Shank2 and Shank3. This suggests an involvement in activity-dependent reorganizations of the cortical actin cytoskeleton necessary for synaptic plasticity.