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ABP 1 - 329 002

An F-Actin binding protein
Polyclonal rabbit antiserum
Cat. No.: 329 002
Amount: 200 µl
Price: 350.00 €
Cat. No. 329 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not recommended
IHC-P/FFPE: not tested yet
Immunogen Synthetic peptide corresponding to AA 1 to 26 from mouse ABP1 (UniProt Id: Q62418)
Reactivity Reacts with: rat (Q9JHL4), mouse (Q62418).
Other species not tested yet.
Specificity Specific for ABP 1.
Data sheet 329_002.pdf
Cat. No.: 329 002
Quantity: 200 µl
Price: 350.00 €
Background

The Actin-binding protein 1 (ABP 1) also known as SH3P7, Dbnl or Debrin-like protein binds to actin filaments especially at sites that represent cellular growth.
In neurons ABP 1 has been shown to interact with the scaffoliding PSD proteins Shank 2 and Shank 3. This suggests an involvement in activity-dependent reorganizations of the cortical actin cytoskeleton necessary for synaptic plasticity.