Cat. No.: 329 002
Amount: 200 µl
Price:
$350.00
| Cat. No. 329 002 | 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. |
| Applications |
WB: 1 : 1000 (AP staining) gallery IP: not tested yet ICC: not tested yet IHC: not recommended IHC-P/FFPE: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 1 to 26 from mouse ABP1 (UniProt Id: Q62418) |
| Reactivity |
Reacts with: rat (Q9JHL4), mouse (Q62418). Other species not tested yet. |
| Specificity | Specific for ABP 1. |
| Data sheet | 329_002.pdf |
 |
The Actin-binding protein 1 (ABP 1) also known as SH3P7, Dbnl or Debrin-like protein binds to actin filaments especially at sites that represent cellular growth.
In neurons ABP 1 has been shown to interact with the scaffoliding PSD proteins Shank 2 and Shank 3. This suggests an involvement in activity-dependent reorganizations of the cortical actin cytoskeleton necessary for synaptic plasticity.
