|Cat. No. 329 002||200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.|
WB: 1 : 1000 (AP staining) gallery
IP: not tested yet
ICC: not tested yet
IHC: not recommended
IHC-P/FFPE: not tested yet
|Immunogen||Synthetic peptide corresponding to AA 1 to 26 from mouse ABP1 (UniProt Id: Q62418)|
Reacts with: rat (Q9JHL4), mouse (Q62418).
Other species not tested yet.
|Specificity||Specific for ABP 1.|
The Actin-binding protein 1 (ABP 1) also known as SH3P7, Dbnl or Debrin-like protein binds to actin filaments especially at sites that represent cellular growth.
In neurons ABP 1 has been shown to interact with the scaffoliding PSD proteins Shank 2 and Shank 3. This suggests an involvement in activity-dependent reorganizations of the cortical actin cytoskeleton necessary for synaptic plasticity.