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Home > Products > 329 002

ABP1 antibody - 329 002

ABP is an F-Actin binding protein
Rabbit polyclonal antiserum
Cat. No.: 329 002
Amount: 200 µl
Price: $355.00
Cat. No. 329 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not recommended
IHC-P: not tested yet

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen Synthetic peptide corresponding to AA 1 to 26 from mouse ABP1 (UniProt Id: Q62418)
Reactivity Reacts with: rat (Q9JHL4), mouse (Q62418).
Other species not tested yet.
Specificity Specific for ABP1.
Data sheet 329_002.pdf
Cat. No.: 329 002
Amount: 200 µl
Price: $355.00
WB
Background

The Actin-binding protein 1 (ABP1) also known as SH3P7, Dbnl or Debrin-like protein binds to actin filaments especially at sites that represent cellular growth.
In neurons ABP1 has been shown to interact with the scaffoliding PSD proteins Shank2 and Shank3. This suggests an involvement in activity-dependent reorganizations of the cortical actin cytoskeleton necessary for synaptic plasticity.