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SATB 2 - 327 004

A transcription factor involved in neuronal differentiation
Polyclonal Guinea pig antiserum
Cat. No.: 327 004
Amount: 100 µl
Price: 350.00 €
Cat. No. 327 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: not recommended
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 718 to 733 from mouse SATB2 (UniProt Id: Q8VI24)
Reactivity Reacts with: rat, mouse (Q8VI24).
Other species not tested yet.
Specificity Specific for SATB 2.
Data sheet 327_004.pdf

References for SATB 2 - 327 004

A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons.
Okaty BW, Sturrock N, Escobedo Lozoya Y, Chang Y, Senft RA, Lyon KA, Alekseyenko OV, Dymecki SM
eLife (2020) 9: . 327 004 IHC; tested species: mouse
Inducing Different Neuronal Subtypes from Astrocytes in the Injured Mouse Cerebral Cortex.
Mattugini N, Bocchi R, Scheuss V, Russo GL, Torper O, Lao CL, Götz M
Neuron (2019) : . 327 004 IHC; tested species: mouse
Cat. No.: 327 004
Quantity: 100 µl
Price: 350.00 €
A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons.
Okaty BW, Sturrock N, Escobedo Lozoya Y, Chang Y, Senft RA, Lyon KA, Alekseyenko OV, Dymecki SM
eLife (2020) 9: . 327 004 IHC; tested species: mouse
Inducing Different Neuronal Subtypes from Astrocytes in the Injured Mouse Cerebral Cortex.
Mattugini N, Bocchi R, Scheuss V, Russo GL, Torper O, Lao CL, Götz M
Neuron (2019) : . 327 004 IHC; tested species: mouse
Background

The Special AT-rich sequence-binding protein 2 or SATB 2 is a transcription factor required for the initiation of the genetic program for the upper-layer neurons (UL1).
Together with Ctip 2, Coup-TFI, and Fezf 2 it is involved in the fine tuned sequential formation and specification of the different excitatory neuron populations forming the definitive six-layered cortical structure.