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Doublecortin antibody - 326 014

Doublecortin or DCX is a protein associated with neuronal differentiation
Guinea pig polyclonal antiserum
Cat. No.: 326 014
Amount: 100 µl
Price: $365.00
Cat. No. 326 014 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
WB: 1 : 2000 up to 1 : 10000 (AP-staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: 1 : 1000 up to 1 : 2000 gallery  
IHC-P: 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to residues near the carboxy terminus of mouse Doublecortin (UniProt Id: Q6PGI2)
Reactivity Reacts with: mouse (O88809).
Other species not tested yet.
Data sheet 326_014.pdf
Cat. No.: 326 014
Amount: 100 µl
Price: $365.00
Doublecortin or DCX seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. Mutations in the gene encoding this protein have been linked to the double cortex syndrome.
Doublecortin is highly expressed in neuronal cells of fetal brain but absent from other tissues. In the adult dentate gyrus it is only expressed in cells contributing to adult neurogenesis.