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Tau - 314 006

A microtubule associated protein
Polyclonal chicken IgY fraction
Cat. No.: 314 006
Amount: 200 µl
Price: $350.00
Cat. No. 314 006 200 µl antibody, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 3 to 214 from mouse Tau-D (UniProt Id: P10637-5)
Reactivity Reacts with: rat, mouse.
Other species not tested yet.
Specificity Specific for tau. Sequence used for immunization is present in all splice variants.
Matching control protein/peptide 314-0P
Remarks

The antibody binds phosphorylated and non-phosphorylated tau proteins.

Data sheet 314_006.pdf
Cat. No.: 314 006
Quantity: 200 µl
Price: $350.00
Background

There are two major classes of heat stable microtubule associated proteins (MAPS): MAP 2 (280 kD), and tau (55-65 kD). Both protein classes are involved in the regulation of microtubule polymerization in cells. Tau is a neuronal protein that mainly localizes to axons. Hyperphosphorylated tau has been shown to be a major element of paired helical filaments in Alzheimer's disease.