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COX 4 antibody - 298 002

COX4 is a protein of the inner mitochondrial membrane
Polyclonal rabbit antiserum
Cat. No.: 298 002
Amount: 200 µl
Price: $350.00
Cat. No. 298 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not recommended
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 1 to 18 from mouse COX4 (UniProt Id: P19783)
Reactivity Reacts with: rat (P10888), mouse (P13073).
Other species not tested yet.
Specificity Specific for COX 4.
Matching control protein/peptide 298-0P
Data sheet 298_002.pdf

References for COX 4 - 298 002

Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity.
Yagensky O, Kohansal-Nodehi M, Gunaseelan S, Rabe T, Zafar S, Zerr I, Härtig W, Urlaub H, Chua JJ
eLife (2019) 8: . 298 002 WB; tested species: mouse
Cat. No.: 298 002
Quantity: 200 µl
Price: $350.00
Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity.
Yagensky O, Kohansal-Nodehi M, Gunaseelan S, Rabe T, Zafar S, Zerr I, Härtig W, Urlaub H, Chua JJ
eLife (2019) 8: . 298 002 WB; tested species: mouse
Background
The enzyme cytochrome C oxidase or Complex 4 is a large heterooligomeric enzyme consisting of 13 subunits. It is localized to the inner mitochondrial membrane. It catalyzes the reduction of molecular oxygen to water coupled to the translocation of protons across the mitochondrial inner membrane. The resulting proton gradient finaly drives ATP synthesis.