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GABA transporter 3 antibody - 274 303

GATs are neurotransmitter transporters involved in the termination of GABA transmission
Polyclonal rabbit purified antibody
Cat. No.: 274 303
Amount: 50 µg
Price: $450.00
Cat. No. 274 303 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 up to 1 : 1000 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 612 to 627 from mouse GABA transporter3 (UniProt Id: P31650)
Reactivity Reacts with: rat (P31647), mouse (P31650).
Other species not tested yet.
Specificity Specific for GAT 3.
Matching control protein/peptide 274-3P
Remarks

WB:  GABA transporter 3 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.

Data sheet 274_303.pdf

References for GABA transporter 3 - 274 303

Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage.
Balzano T, Leone P, Ivaylova G, Castro MC, Reyes L, Ramón C, Malaguarnera M, Llansola M, Felipo V
Biomedicines (2021) 98: . 274 303 WB; tested species: rat
Cat. No.: 274 303
Quantity: 50 µg
Price: $450.00
Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage.
Balzano T, Leone P, Ivaylova G, Castro MC, Reyes L, Ramón C, Malaguarnera M, Llansola M, Felipo V
Biomedicines (2021) 98: . 274 303 WB; tested species: rat
Background
γ-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. After the release of GABA from synaptic vesicles into the synaptic cleft during neurotransmission, GABA transporters (GATs) remove extracellular GABA by reuptake into the presynaptic terminal.
Three GABA transporters are described so far of which only GAT 1 and GAT 3 are expressed in the brain.