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Home > Products > 262 013

CAPS1 antibody - 262 013 K.O.

CAPS1 is a Ca2+-dependent secretion activator
Rabbit polyclonal purified antibody
Cat. No.: 262 013
Amount: 50 µg
Price: $380.00
Cat. No. 262 013 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (see remarks)
IP: not tested yet
ICC: 1 : 200 up to 1 : 500 gallery  
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 18 to 107 from mouse CAPS1 (UniProt Id: Q80TJ1)
Reactivity Reacts with: rat (Q62717), mouse (Q80TJ1).
Other species not tested yet.
Specificity Specific for CAPS 1, no cross-reactvity to CAPS 2 K.O. validated PubMed: 25719439
Remarks

WB: Cat. no. 262 003 is recommended for this application.
Data sheet 262_013.pdf

References for CAPS1 - 262 013

Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission.
Lipstein N, Chang S, Lin KH, López-Murcia FJ, Neher E, Taschenberger H, Brose N
Neuron (2021) : . 262 013 WB; tested species: mouse
Paralogs of the Calcium-Dependent Activator Protein for Secretion Differentially Regulate Synaptic Transmission and Peptide Secretion in Sensory Neurons.
Shaib AH, Staudt A, Harb A, Klose M, Shaaban A, Schirra C, Mohrmann R, Rettig J, Becherer U
Frontiers in cellular neuroscience (2018) 12: 304. 262 013 WB, ICC; KO verified; tested species: mouse
Cat. No.: 262 013
Amount: 50 µg
Price: $380.00
ICC
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