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CAPS 1 antibody - 262 003

CAPS1 is a Ca2+-dependent secretion activator
Polyclonal rabbit purified antibody
Cat. No.: 262 003
Amount: 50 µg
Price: $370.00
Cat. No. 262 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 500 up to 1 : 1000 gallery  
IP: yes
ICC: not tested yet
IHC: yes
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 18 to 107 from mouse CAPS1 (UniProt Id: Q80TJ1)
Reactivity Reacts with: rat (Q62717), mouse (Q80TJ1).
Other species not tested yet.
Specificity Specific for CAPS 1, no cross-reactvity to CAPS 2 K.O.
Data sheet 262_003.pdf

References for CAPS 1 - 262 003

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.
Vogl C, Cooper BH, Neef J, Wojcik SM, Reim K, Reisinger E, Brose N, Rhee JS, Moser T, Wichmann C
Journal of cell science (2015) 1284: 638-44. 262 003 IHC
Cat. No.: 262 003
Quantity: 50 µg
Price: $370.00
Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.
Vogl C, Cooper BH, Neef J, Wojcik SM, Reim K, Reisinger E, Brose N, Rhee JS, Moser T, Wichmann C
Journal of cell science (2015) 1284: 638-44. 262 003 IHC
Background
The Ca2+-dependent activator protein for secretion (CAPS) regulates exocytosis of catecholamine- or neuropeptide-containing dense-core vesicles (DCVs) at secretion sites.
Two differen isoforms CAPS 1/CADPS 1 and CAPS 2/CADPS 2 that are mainly expressed in brain have been identified in mammals. Both have been shown to be essential components of the synaptic vesicle priming machinery.