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Collybistin antibody - 261 111

Collybistin is a protein involved in gephyrin clustering
Monoclonal mouse purified IgG
Cat. No.: 261 111
Amount: 100 µg
Price: $415.00
Cat. No. 261 111 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: not recommended
IP: yes
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: not tested yet
Clone 197A10
Subtype IgG2b (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 471 from rat Collybistin (UniProt Id: Q9QX73)
Epitop Epitop: AA 4 to 229 from rat Collybistin (UniProt Id: Q9QX73)
Reactivity Reacts with: rat (Q9QX73), mouse (Q3UTH8).
Other species not tested yet.
Specificity Specific for collybistin, immunogen present in all three described splice-variants.
Data sheet 261_111.pdf
Cat. No.: 261 111
Quantity: 100 µg
Price: $415.00
Background

The GDP/GTP-exchange factor collybistin is composed of a dbl homology domain (DH) and a pleckstrin homology domain (PH) connected by a linker sequence. Three splice variants with different C-terminal regions have been described, so far.
Collybistin is supposed to be involved in the clustering of gephyrin, a scaffolding protein linking glycine and GABA receptors to microtubuli.