|Cat. No. 261 111||100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.|
WB: not recommended
ICC: 1 : 500 gallery
IHC: not tested yet
IHC-P/FFPE: not tested yet
|Subtype||IgG2b (κ light chain)|
|Immunogen||Recombinant protein corresponding to AA 1 to 471 from rat Collybistin (UniProt Id: Q9QX73)|
Epitop: AA 4 to 229 from rat Collybistin (UniProt Id: Q9QX73)
Reacts with: rat (Q9QX73), mouse (Q3UTH8).
Other species not tested yet.
|Specificity||Specific for collybistin, immunogen present in all three described splice-variants.|
The GDP/GTP-exchange factor collybistin is composed of a dbl homology domain (DH) and a pleckstrin homology domain (PH) connected by a linker sequence. Three splice variants with different C-terminal regions have been described, so far.
Collybistin is supposed to be involved in the clustering of gephyrin, a scaffolding protein linking glycine and GABA receptors to microtubuli.