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Collybistin antibody - 261 011

Collybistin is a protein involved in gephyrin clustering
Monoclonal mouse purified IgG
Cat. No.: 261 011
Amount: 100 µg
Price: $415.00
Cat. No. 261 011 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (ECL detection) gallery  
IP: not recommended
ICC: not recommended
IHC: not recommended
IHC-P/FFPE: not tested yet
Clone 161B11
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 471 from rat Collybistin (UniProt Id: Q9QX73)
Epitop Epitop: AA 4 to 229 from rat Collybistin (UniProt Id: Q9QX73)
Reactivity Reacts with: rat (Q9QX73), mouse (Q3UTH8).
Other species not tested yet.
Specificity Specific for collybistin, immunogen present in all three described splice-variants. K.O.
Data sheet 261_011.pdf

References for Collybistin - 261 011

Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes.
Schäfer J, Förster L, Mey I, Papadopoulos T, Brose N, Steinem C
The Journal of biological chemistry (2020) : . 261 011 WB
Cat. No.: 261 011
Quantity: 100 µg
Price: $415.00
Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes.
Schäfer J, Förster L, Mey I, Papadopoulos T, Brose N, Steinem C
The Journal of biological chemistry (2020) : . 261 011 WB
Background

The GDP/GTP-exchange factor collybistin is composed of a dbl homology domain (DH) and a pleckstrin homology domain (PH) connected by a linker sequence. Three splice variants with different C-terminal regions have been described, so far.
Collybistin is supposed to be involved in the clustering of gephyrin, a scaffolding protein linking glycine and GABA receptors to microtubuli.