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Home > Products > 249-0P

VAP-A protein - 249-0P

VAP-A is a SNARE binding protein
control protein
Cat. No.: 249-0P
Amount: 100 µg
Price: $105.00
Cat. No. 249-0P 100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control proteins should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
Immunogen Recombinant protein corresponding to AA 1 to 223 from human VAP-A (UniProt Id: Q9P0L0)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 249 002, 249 003
Remarks

This control protein consists of the recombinant protein (aa 1-223 of human VAP-A) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
Data sheet 249-0p.pdf
Cat. No.: 249-0P
Amount: 100 µg
Price: $105.00
Background
The VAMP-associated protein A VAP-A, also referred to as VAP-33, is a ubiquitously expressed type IV membrane protein. It is composed of an N-terminal domain with an immunoglobulin-like b-sheet, a central coiled-coiled domain and a C-terminal transmembrane domain. The protein, which may be involved in vesicle trafficking, is located to the endoplasmic reticulum (ER) and ER/Golgi intermediate compartment (ERGIC). VAP-A has been shown to bind to dfifferent v- and t-SNARE proteins.
Two other isoforms, VAP-B and VAP-C, have been described in the literature so far.
Protocols
OTHER
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