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M6a Glycoprotein - 238 003

A neuron specific PLP family member
Polyclonal rabbit purified antibody
Cat. No.: 238 003
Amount: 50 µg
Price: $370.00
Cat. No. 238 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 1000 gallery  
IHC: 1 : 200 gallery  
IHC-P/FFPE: 1 : 200 gallery  
Immunogen Synthetic peptide corresponding to AA 261 to 270 from rat M6a Glycoprotein (UniProt Id: Q812E9)
Reactivity Reacts with: human (P51674), rat (Q812E9), mouse (P35802), pig, dog, zebrafish.
Other species not tested yet.
Specificity Specific for M6a neuronal glycoprotein.
Matching control protein/peptide 238-0P
Data sheet 238_003.pdf
Cat. No.: 238 003
Quantity: 50 µg
Price: $370.00
Background
M6a and M6b are transmembrane glycoproteins with four membrane spanning domains that belong to the myelin proteolipid protein (PLP) family. In contrast to other PLP proteins that are expressed by glia cells, M6a is found only in neurons where it is concentrated at presynaptic glutamateric terminals.
M6a has been suggested to be a potential mediator of cell-cell interactions involved in axonfasciculation during development.