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BNIP 1 - 227 003

A member of the syntaxin 18 complex
Polyclonal rabbit purified antibody
Cat. No.: 227 003
Amount: 50 µg
Price: $370.00
Cat. No. 227 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 5 to 105 from mouse BNIP1 (UniProt Id: Q6QD59)
Reactivity Reacts with: rat (Q8VHI8), mouse (Q6QD59).
Other species not tested yet.
Specificity Specific for BNIP 1, antigen present in all 4 splice variants.
Data sheet 227_003.pdf

References for BNIP 1 - 227 003

Activity of the SNARE Protein SNAP29 at the Endoplasmic Reticulum and Golgi Apparatus.
Morelli E, Speranza EA, Pellegrino E, Beznoussenko GV, Carminati F, Garré M, Mironov AA, Onorati M, Vaccari T
Frontiers in cell and developmental biology (2021) 9: 637565. 227 003 WB; tested species: human
Cat. No.: 227 003
Quantity: 50 µg
Price: $370.00
Activity of the SNARE Protein SNAP29 at the Endoplasmic Reticulum and Golgi Apparatus.
Morelli E, Speranza EA, Pellegrino E, Beznoussenko GV, Carminati F, Garré M, Mironov AA, Onorati M, Vaccari T
Frontiers in cell and developmental biology (2021) 9: 637565. 227 003 WB; tested species: human
Background

BNIPs belong to the proapoptotic BH3-only protein family. Three isoforms have been described so far. BNIP 1 is involved in the maintenance of ER-integrity. It is a member of the syntaxin 18 complex which is involved in membrane trafficking between the ER and Golgi. Four different BNIP 1 splice variants have been described so far, one of which contains a highly conserved BH3 domain. All BNIP 1 variants are able to interact with the apoptosis regulators BCL2 and BCL2L1.