Cat. No.: 224 104
Amount: 100 µl
Price:
350.00 €
| Cat. No. 224 104 | 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. |
| Applications |
WB: 1 : 1000 (AP staining) (see remarks) gallery IP: yes ICC: 1 : 200 up to 1 : 500 (see remarks) gallery IHC: not tested yet IHC-P/FFPE: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 29 to 37 from rat GABA-A receptor α2 (UniProt Id: P23576) |
| Reactivity |
Reacts with: human (P47869), rat (P23576), mouse (P26048). Other species not tested yet. |
| Specificity | Specific for GABA-A receptor α2. |
| Matching control protein/peptide | 224-1P |
| Remarks |
WB: GABA-A receptor alpha2 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples. ICC: This antibody is also suitable for the surface staining of living cells. After washing cells with bound antibodies, they can be fixed and visualized with secondary reagents. |
| Data sheet | 224_104.pdf |
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Gamma-aminobutyric acid type A (GABA-A) receptors mediate the majority of inhibitory neurotransmission in the brain. These receptor proteins are ligand gated chloride ion channels and consist of a pentameric combination of different subunits (alpha, beta, gamma, delta, epsilon and rho). The resulting heterogenous population of GABA-A receptor subtypes are expressed throughout the brain with specific cellular and subcellular expression patterns.
