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Home > Products > 217 011

Tenascin-R antibody - 217 011 K.O.

Tenascin-R is a multidomain adhesion molecule
Mouse monoclonal purified IgG
Cat. No.: 217 011
Amount: 100 µg
Price: $415.00
Cat. No. 217 011 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: not recommended
EM: yes
Clone 619
Subtype IgG1 (κ light chain)
Immunogen full length bovine Tenascin-R isolated from brain
Reactivity Reacts with: rat (Q05546), mouse (Q8BYI9), cow, chicken.
Other species not tested yet.
Specificity K.O. validated PubMed: 16870730
Data sheet 217_011.pdf

References for Tenascin-R - 217 011

Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.
Weber P, Bartsch U, Rasband MN, Czaniera R, Lang Y, Bluethmann H, Margolis RU, Levinson SR, Shrager P, Montag D, Schachner M, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (1999) 1911: 4245-62. 217 011 WB, IHC; KO verified
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence.
Kohnke S, Buller S, Nuzzaci D, Ridley K, Lam B, Pivonkova H, Bentsen MA, Alonge KM, Zhao C, Tadross J, Holmqvist S, et al.
Cell reports (2021) 362: 109362. 217 011 IHC; tested species: mouse
Synaptic coupling of inner ear sensory cells is controlled by brevican-based extracellular matrix baskets resembling perineuronal nets.
Sonntag M, Blosa M, Schmidt S, Reimann K, Blum K, Eckrich T, Seeger G, Hecker D, Schick B, Arendt T, Engel J, et al.
BMC biology (2018) 161: 99. 217 011 IHC; tested species: mouse
Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space.
Arranz AM, Perkins KL, Irie F, Lewis DP, Hrabe J, Xiao F, Itano N, Kimata K, Hrabetova S, Yamaguchi Y
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3418: 6164-76. 217 011 IHC; tested species: mouse
Tenascin-R restricts posttraumatic remodeling of motoneuron innervation and functional recovery after spinal cord injury in adult mice.
Apostolova I, Irintchev A, Schachner M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7849-59. 217 011 IHC; KO verified; tested species: mouse
Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R.
Brückner G, Grosche J, Schmidt S, Härtig W, Margolis RU, Delpech B, Seidenbecher CI, Czaniera R, Schachner M
The Journal of comparative neurology (2000) 4284: 616-29. 217 011 IHC; KO verified; tested species: mouse
Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.
Weber P, Bartsch U, Rasband MN, Czaniera R, Lang Y, Bluethmann H, Margolis RU, Levinson SR, Shrager P, Montag D, Schachner M, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (1999) 1911: 4245-62. 217 011 WB, IHC; KO verified
The distribution of tenascin-R in the developing avian nervous system.
Derr LB, McKae LA, Tucker RP
The Journal of experimental zoology (1998) 2802: 152-64. 217 011 IHC; tested species: chicken
Isolation of a tenascin-R binding protein from mouse brain membranes. A phosphacan-related chondroitin sulfate proteoglycan.
Xiao ZC, Bartsch U, Margolis RK, Rougon G, Montag D, Schachner M
The Journal of biological chemistry (1997) 27251: 32092-101. 217 011 IHC; tested species: mouse
Immunoelectron microscopic localization of the neural recognition molecules L1, NCAM, and its isoform NCAM180, the NCAM-associated polysialic acid, beta1 integrin and the extracellular matrix molecule tenascin-R in synapses of the adult rat hippocampus.
Schuster T, Krug M, Stalder M, Hackel N, Gerardy-Schahn R, Schachner M
Journal of neurobiology (2001) 492: 142-58. 217 011 EM
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Cat. No.: 217 011
Amount: 100 µg
Price: $415.00
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.
Weber P, Bartsch U, Rasband MN, Czaniera R, Lang Y, Bluethmann H, Margolis RU, Levinson SR, Shrager P, Montag D, Schachner M, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (1999) 1911: 4245-62. 217 011 WB, IHC; KO verified
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence.
Kohnke S, Buller S, Nuzzaci D, Ridley K, Lam B, Pivonkova H, Bentsen MA, Alonge KM, Zhao C, Tadross J, Holmqvist S, et al.
Cell reports (2021) 362: 109362. 217 011 IHC; tested species: mouse
Synaptic coupling of inner ear sensory cells is controlled by brevican-based extracellular matrix baskets resembling perineuronal nets.
Sonntag M, Blosa M, Schmidt S, Reimann K, Blum K, Eckrich T, Seeger G, Hecker D, Schick B, Arendt T, Engel J, et al.
BMC biology (2018) 161: 99. 217 011 IHC; tested species: mouse
Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space.
Arranz AM, Perkins KL, Irie F, Lewis DP, Hrabe J, Xiao F, Itano N, Kimata K, Hrabetova S, Yamaguchi Y
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3418: 6164-76. 217 011 IHC; tested species: mouse
Tenascin-R restricts posttraumatic remodeling of motoneuron innervation and functional recovery after spinal cord injury in adult mice.
Apostolova I, Irintchev A, Schachner M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2630: 7849-59. 217 011 IHC; KO verified; tested species: mouse
Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R.
Brückner G, Grosche J, Schmidt S, Härtig W, Margolis RU, Delpech B, Seidenbecher CI, Czaniera R, Schachner M
The Journal of comparative neurology (2000) 4284: 616-29. 217 011 IHC; KO verified; tested species: mouse
Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.
Weber P, Bartsch U, Rasband MN, Czaniera R, Lang Y, Bluethmann H, Margolis RU, Levinson SR, Shrager P, Montag D, Schachner M, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (1999) 1911: 4245-62. 217 011 WB, IHC; KO verified
The distribution of tenascin-R in the developing avian nervous system.
Derr LB, McKae LA, Tucker RP
The Journal of experimental zoology (1998) 2802: 152-64. 217 011 IHC; tested species: chicken
Isolation of a tenascin-R binding protein from mouse brain membranes. A phosphacan-related chondroitin sulfate proteoglycan.
Xiao ZC, Bartsch U, Margolis RK, Rougon G, Montag D, Schachner M
The Journal of biological chemistry (1997) 27251: 32092-101. 217 011 IHC; tested species: mouse
Immunoelectron microscopic localization of the neural recognition molecules L1, NCAM, and its isoform NCAM180, the NCAM-associated polysialic acid, beta1 integrin and the extracellular matrix molecule tenascin-R in synapses of the adult rat hippocampus.
Schuster T, Krug M, Stalder M, Hackel N, Gerardy-Schahn R, Schachner M
Journal of neurobiology (2001) 492: 142-58. 217 011 EM
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, et al.
Nature communications (2021) 121: 7129. 217 011 WB, IP, ICC, IHC, UPTAKE; KO,KD verified; tested species: mouse,rat
WB
ICC
IHC
IHC
Background
Tenascin-R, also referred to as TNR and J1-160/180, is an extracellular matrix glycoprotein expressed by oligodendrocytes and subpopulations of neurons in the adult CNS of vertebrates. TNR is a member of the Tenascin family of multidomain adhesion molecules and affects neuronal cell migration and neurite extension.
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