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Tyrosine hydroxylase antibody - 213 308

Tyrosine hydroxylase is the rate limiting enzyme in catecholamine synthesis
Guinea pig monoclonal recombinant IgG
Cat. No.: 213 308
Amount: 50 µg
Price: $415.00
Cat. No. 213 308 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
WB: 1 : 1000 (AP-staining) (see remarks) gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 10000 gallery  
IHC-P: 1 : 5000 up to 1 : 10000 gallery  
Clone Gp103E1
Subtype IgG2 (κ light chain)
Immunogen Recombinant protein corresponding to residues near the amino-terminus of rat TyrH. (UniProt Id: P04177)
Epitop Epitop: AA 65 to 163 from rat TyrH (UniProt Id: P04177)
Reactivity Reacts with: rat (P04177), mouse (P24529).
Other species not tested yet.

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 103E1. The constant regions of the heavy and light chains have been replaced by guinea pig specific sequences. Therefore, the antibody can be used with standard anti-guinea pig secondary reagents. The antibody has been expressed in mammalian cells.
WB: This antibody is less sensitive than our polyclonal antibodies (cat. no. 213 102 and 213 104).

Data sheet 213_308.pdf
Cat. No.: 213 308
Amount: 50 µg
Price: $415.00
Tyrosine hydroxylase is one of the key enzymes in the synthesis pathway of catecholamines like adrenalin, noradrenalin and dopamin and is frequently used as a marker for dopaminergic neurons. This neuronal subpopulation is especially affected in Parkinson's disease.