Cat. No.: 192 104
Amount: 100 µl
Price:
$365.00
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| Cat. No. 192 104 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 95 to 207 from rat Ribeye (UniProt Id: Q9EQH5-2) |
| Reactivity |
Reacts with: rat (Q9EQH5-2), mouse (P56546-2). Other species not tested yet. |
| Specificity | This antibody recognizes only ribeye and not CtBP 2. |
| Remarks |
IHC: For optimal results, mild fixation (immersion fixation with 4% PFA for 15 min) according to Gierke et al. 2023 or Klotz et al. 2019 is recommended. |
| Data sheet | 192_104.pdf |
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The photoreceptor ribbon synapse is a unique type of synapse specialized for the tonic release of neurotransmitter in the dark. Ribeye is a self-aggregating protein and is one of the major scaffolding components of the ribbon on which the neurotransmitter containing vesicles are tethered. The protein consists of a unique A-domain and a B-domain. With the exception of the first 20 amino acids the B-domain is identical to the transcriptional corepressor CtBP 2. Both proteins originate from the same gene.