Cat. No.: 182 111
Amount: 100 µg
Price:
$415.00
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| Cat. No. 182 111 |
100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | 1404A10 |
| Subtype | IgG2b (κ light chain) |
| Immunogen | Synthetic peptide corresponding to AA 278 to 292 from rat GluA2 (UniProt Id: P19491) |
| Reactivity |
Reacts with: rat (P19491), mouse (P23819), human (P42262). No signal: zebrafish. Other species not tested yet. |
| Remarks |
IP: For most effective IP, use the denaturing IP-protocol. Consider that protein-protein interactions may be affected. |
| Data sheet | 182_111.pdf |
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Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.