Cat. No.: 182 008
Amount: 50 µg
Price:
$415.00
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| Cat. No. 182 008 |
50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | Rb4G7 |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Recombinant protein corresponding to residues near the carboxy terminus of rat GluA2 (UniProt Id: P19491) |
| Reactivity |
Reacts with: mouse (P23819), rat (P19491). Other species not tested yet. |
| Matching control protein/peptide | 182-1P |
| Remarks |
This antibody is a chimeric antibody based on the monoclonal rat antibody SY-4G7. The constant regions of the heavy and light chains have been replaced with rabbit specific sequences. The antibody can therefore be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells. |
| Data sheet | 182_008.pdf |
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Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN and kainate/GluK receptors (KARs). mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins.
Glutamate receptors of the AMPA subtype are monovalent cation channels and are composed of the four AMPA subunits GluA 1, GluA 2, GluA 3, and GluA 4.