Cat. No.: 169 102
Amount: 200 µl
Price:
$355.00
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| Cat. No. 169 102 |
200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 463 to 604 from mouse Liprin-α3 (UniProt Id: P60469) |
| Reactivity |
Reacts with: human (O75145), rat (Q91Z79), mouse (P60469). No signal: zebrafish. Other species not tested yet. |
| Specificity | Specific for liprin-α 3, no cross reaction to isoforms 1, 2, 4. |
| Matching control protein/peptide | 169-1P |
| Data sheet | 169_102.pdf |
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The liprin-α/Syd 2 protein family was initially identified as binding partners of the LAR family of receptor protein-tyrosine phosphatases.
Liprin-α proteins are multidomain proteins which are involved in the development of presynaptic active zones. Four isoforms of liprin-α have been described, so far and all of them interact with the RIM binding partners ERC 1b and ERC 2.
All four isoforms of liprin-α have also been identified as members of the MALS complex composed of CASK, Mint1 and Velis. This complex has been reported to be crucial for synaptic vesicle exocytosis.