Tailor-made Antibodies
and Tools for Life Science

Synaptopodin antibody - 163 002 K.O.

Synaptopodin is an actin associated protein present in renal podocytes and telencephalic dendrites
Rabbit polyclonal antiserum
Cat. No.: 163 002
Amount: 200 µl
Price: $360.00
Cat. No. 163 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 600 gallery  
IHC: 1 : 250 up to 1 : 500 gallery  
IHC-P: 1 : 250 up to 1 : 500 gallery  
Immunogen Recombinant protein corresponding to residues near the central region of mouse Synaptopodin. (UniProt Id: Q8CC35)
Reactivity Reacts with: human (Q8N3V7), rat (Q9Z327), mouse (Q8CC35).
Other species not tested yet.
Specificity This antibody detects the renal Synpo-long and the neuronal Synpo-short isofoms but is negativ for the T-variant. K.O. validated
Matching control protein/peptide 163-0P
Data sheet 163_002.pdf

References for Synaptopodin - 163 002

Expression of synaptic proteins and development of dendritic spines in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa.
Sobierajski E, Czubay K, Schmidt MR, Wiedenski S, Rettschlag S, Beemelmans C, Beemelmans C, Wahle P
Brain structure & function (2025) 2302: 38. 163 002 WB; tested species: pig
EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation.
Ha KB, Sangartit W, Jeong AR, Lee ES, Kim HM, Shim S, Kukongviriyapan U, Kim DK, Lee EY, Chung CH
Endocrinology and metabolism (Seoul, Korea) (2022) 371: 96-111. 163 002 WB; tested species: mouse
miR-124-dependent tagging of synapses by synaptopodin enables input-specific homeostatic plasticity.
Dubes S, Soula A, Benquet S, Tessier B, Poujol C, Favereaux A, Thoumine O, Letellier M
The EMBO journal (2022) : e109012. 163 002 WB, ICC; tested species: rat
Proteome dynamics during homeostatic scaling in cultured neurons.
Dörrbaum AR, Alvarez-Castelao B, Nassim-Assir B, Langer JD, Schuman EM
eLife (2020) 9: . 163 002 WB; tested species: rat
Synaptopodin is regulated by aromatase activity.
Fester L, Zhou L, Ossig C, Labitzke J, Bläute C, Bader M, Vollmer G, Jarry H, Rune GM
Journal of neurochemistry (2017) 1401: 126-139. 163 002 WB, ICC, IHC
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting.
Biesemann C, Grønborg M, Luquet E, Wichert SP, Bernard V, Bungers SR, Cooper B, Varoqueaux F, Li L, Byrne JA, Urlaub H, et al.
The EMBO journal (2014) 332: 157-70. 163 002 WB; tested species: mouse
Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.
Borlikova GG, Trejo M, Mably AJ, Mc Donald JM, Sala Frigerio C, Regan CM, Murphy KJ, Masliah E, Walsh DM
Neurobiology of aging (2013) 345: 1315-27. 163 002 WB; tested species: rat
Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain.
Cohen JW, Louneva N, Han LY, Hodes GE, Wilson RS, Bennett DA, Lucki I, Arnold SE
Synapse (New York, N.Y.) (2011) 658: 763-70. 163 002 WB, IHC
Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons.
Vlachos A, Korkotian E, Schonfeld E, Copanaki E, Deller T, Segal M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2009) 294: 1017-33. 163 002 WB, ICC
Cat. No.: 163 002
Amount: 200 µl
Price: $360.00