Synaptic Systems

Cat. No.: 162 211

Amount: 100 µg

Price: $420.00

Cat. No. 162 211	100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: not recommended IP: not tested yet ICC: 1 : 500 gallery IHC: 1 : 500 (see remarks) gallery IHC-P: not recommended IHC-Fr: 1 : 500 (see remarks) gallery
Clone	298F5
Subtype	IgG1 (κ light chain)
Immunogen	Recombinant protein corresponding to residues near the carboxy terminus of rat Shank2 (UniProt Id: Q9QX74)
Reactivity	Reacts with: rat (Q9QX74). Other species not tested yet.
Remarks	IHC: Fix for 15 min with 4% PFA and 15% picric acid in PBS. IHC-Fr: Fixation with acetone or PFA/formaldehyde is recommended. Postfixation with methanol is not advised.
Data sheet	162_211.pdf

Mecp2 knock-out astrocytes affect synaptogenesis by interleukin 6 dependent mechanisms.
Albizzati E, Breccia M, Florio E, Cabasino C, Postogna FM, Grassi R, Boda E, Battaglia C, De Palma C, De Quattro C, Pozzi D, et al.
iScience (2024) 273: 109296. 162 211 ICC; tested species: mouse

GM1 Oligosaccharide Ameliorates Rett Syndrome Phenotypes In Vitro and In Vivo via Trk Receptor Activation.
Fazzari M, Lunghi G, Carsana EV, Valsecchi M, Spiombi E, Breccia M, Casati SR, Pedretti S, Mitro N, Mauri L, Ciampa MG, et al.
International journal of molecular sciences (2024) 2521: . 162 211 ICC; tested species: mouse

Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway.
Frasca A, Miramondi F, Butti E, Indrigo M, Balbontin Arenas M, Postogna FM, Piffer A, Bedogni F, Pizzamiglio L, Cambria C, Borello U, et al.
EMBO molecular medicine (2024) 1612: 3218-3246. 162 211 ICC; tested species: mouse

Cat. No.: 162 211

Amount: 100 µg

Price: $420.00

ICC

IHC

IHC-Fr

Background

Protocols

Shank2 antibody - 162 211