Tailor-made Antibodies
and Tools for Life Science

Endophilin1 antibody - 159 002 K.O.

Endophilin1 is an SH3 domain protein involved in clathrin mediated endocytosis
Rabbit polyclonal antiserum
Cat. No.: 159 002
Amount: 200 µl
Price: $360.00
Cat. No. 159 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 10000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 200 gallery  
IHC-P: 1 : 1000 gallery  
Immunogen Synthetic peptide corresponding to AA 256 to 276 from mouse Endophilin1 (UniProt Id: Q62420)
Reactivity Reacts with: rat (O35179), mouse (Q62420).
Other species not tested yet.
Specificity K.O. validated PubMed: 29892212
Matching control protein/peptide 159-0P
Data sheet 159_002.pdf

References for Endophilin1 - 159 002

Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson's disease.
Vidyadhara DJ, Somayaji M, Wade N, Yücel B, Zhao H, Shashaank N, Ribaudo J, Gupta J, Lam TT, Sames D, Greene LE, et al.
Cell reports (2023) 423: 112231. 159 002 WB, IHC; tested species: mouse
A novel synaptopathy-defective synaptic vesicle protein trafficking in the mutant CHMP2B mouse model of frontotemporal dementia.
Clayton EL, Bonnycastle K, Isaacs AM, Cousin MA, Schorge S
Journal of neurochemistry (2022) 1603: 412-425. 159 002 WB; tested species: mouse
Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.
Azarnia Tehran D, Kochlamazashvili G, Pampaloni NP, Sposini S, Shergill JK, Lehmann M, Pashkova N, Schmidt C, Löwe D, Napieczynska H, Heuser A, et al.
Science advances (2022) 821: eabl5032. 159 002 WB; tested species: mouse
Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.
Gorenberg EL, Massaro Tieze S, Yücel B, Zhao HR, Chou V, Wirak GS, Tomita S, Lam TT, Chandra SS
PLoS biology (2022) 203: e3001590. 159 002 WB; tested species: mouse
Reduced dynamin-1 levels in neurons lacking MUNC18-1.
Lammertse HCA, Moro A, Saarloos I, Toonen RF, Verhage M
Journal of cell science (2022) 13522: . 159 002 WB; tested species: mouse
Synaptic AP2 CCV life cycle regulation by the Eps15, ITSN1, Sgip1/AP2, synaptojanin1 interactome.
Mishra R, Sengül GF, Candiello E, Schu P
Scientific reports (2021) 111: 8007. 159 002 WB; tested species: mouse
VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context.
Richter K, Schmutz I, Darna M, Zander JF, Chavan R, Albrecht U, Ahnert-Hilger G
Neuroscience (2018) 371: 29-37. 159 002 WB; tested species: mouse
Endophilin A1 Promotes Actin Polymerization in Dendritic Spines Required for Synaptic Potentiation.
Yang Y, Chen J, Guo Z, Deng S, Du X, Zhu S, Ye C, Shi YS, Liu JJ
Frontiers in molecular neuroscience (2018) 11: 177. 159 002 WB, ICC, IHC; KO verified; tested species: mouse
Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons.
Cao M, Wu Y, Ashrafi G, McCartney AJ, Wheeler H, Bushong EA, Boassa D, Ellisman MH, Ryan TA, De Camilli P
Neuron (2017) 934: 882-896.e5. 159 002 WB; tested species: mouse
Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.
Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G
ACS chemical neuroscience (2017) 85: 1101-1116. 159 002 WB; tested species: mouse,rat
Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis.
Ahmad G, Mohapatra BC, Schulte NA, Nadeau SA, Luan H, Zutshi N, Tom E, Ortega-Cava C, Tu C, Sanada M, Ogawa S, et al.
The international journal of biochemistry & cell biology (2014) 57: 123-34. 159 002 WB; tested species: mouse
A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons.
Wahl S, Katiyar R, Schmitz F
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3325: 10278-300. 159 002 WB, ICC
Cat. No.: 159 002
Amount: 200 µl
Price: $360.00