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CASK antibody - 150 002

CASK is a MAGUK family protein of the pre-synaptic active zone
Polyclonal rabbit antiserum
Cat. No.: 150 002
Amount: 200 µl
Price: $350.00
Cat. No. 150 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 100 up to 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 337 from rat CASK (UniProt Id: Q62915)
Reactivity Reacts with: rat (Q62915), mouse (O70589), hamster.
Other species not tested yet.
Specificity Specific for CASK.
Data sheet 150_002.pdf

References for CASK - 150 002

The proteome of the presynaptic active zone: from docked synaptic vesicles to adhesion molecules and maxi-channels.
Morciano M, Beckhaus T, Karas M, Zimmermann H, Volknandt W
Journal of neurochemistry (2009) 1083: 662-75. 150 002 WB
Cat. No.: 150 002
Quantity: 200 µl
Price: $350.00
The proteome of the presynaptic active zone: from docked synaptic vesicles to adhesion molecules and maxi-channels.
Morciano M, Beckhaus T, Karas M, Zimmermann H, Volknandt W
Journal of neurochemistry (2009) 1083: 662-75. 150 002 WB
Background

CASK, like PSD 95, belongs to the family of membrane associated guanylate kinase homologues (MAGUKs) but contains an additional N-terminal CaM kinase-like domain.
It has been shown to interact with Mint and Veli via its N-terminal domains. PDZ domains are present in all three proteins of the complex. They are free to recruit other proteins like neurexins and syndecans. The complex of CASK, Velis and Mint is conserved across kingdoms and has also been observed in C. elegans.