Tailor-made Antibodies
and Tools for Life Science

Snapin antibody - 148 002 K.O.

Snapin is involved in SNARE mediated vesicle fusion
Rabbit polyclonal antiserum
Cat. No.: 148 002
Amount: 200 µl
Price: $360.00
Cat. No. 148 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 100 up to 1 : 5000
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 1 to 136 from rat Snapin (UniProt Id: P60192)
Reactivity Reacts with: human (O95295), rat (P60192), mouse (Q9Z266), rabbit.
No signal: zebrafish.
Other species not tested yet.
Specificity K.O. validated PubMed: 20946101
Matching control protein/peptide 148-0P
Remarks

Since snapin is present in very low concentrations long exposure time is recommended.

Data sheet 148_002.pdf

References for Snapin - 148 002

Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells.
Matsui T, Sakamaki Y, Nakashima S, Fukuda M
Cell reports (2022) 399: 110875. 148 002 WB; tested species: human
A Ragulator-BORC interaction controls lysosome positioning in response to amino acid availability.
Pu J, Keren-Kaplan T, Bonifacino JS
The Journal of cell biology (2017) 21612: 4183-4197. 148 002 WB; tested species: human
Dysbindin-associated proteome in the p2 synaptosome fraction of mouse brain.
Han MH, Hu Z, Chen CY, Chen Y, Gucek M, Li Z, Markey SP
Journal of proteome research (2014) 1311: 4567-80. 148 002 WB; tested species: mouse
Snapin, positive regulator of stimulation- induced Ca²⁺ release through RyR, is necessary for HIV-1 replication in T cells.
Kinoshita SM, Kogure A, Taguchi S, Nolan GP
PloS one (2013) 810: e75297. 148 002 WB, IP, ICC; tested species: human
LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25.
Yun HJ, Park J, Ho DH, Kim H, Kim CH, Oh H, Ga I, Seo H, Chang S, Son I, Seol W, et al.
Experimental & molecular medicine (2013) 45: e36. 148 002 IP, WB; tested species: mouse
Snapin deficiency is associated with developmental defects of the central nervous system.
Zhou B, Zhu YB, Lin L, Cai Q, Sheng ZH
Bioscience reports (2011) 312: 151-8. 148 002 WB; KO verified; tested species: mouse
The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells.
Ginter-Matuszewska B, Spik A, Rembiszewska A, Koyias C, Kupryjanczyk J, Jaruzelska J
Molecular human reproduction (2009) 153: 173-9. 148 002 WB, IHC-P; tested species: human,mouse
Snapin interacts with the Exo70 subunit of the exocyst and modulates GLUT4 trafficking.
Bao Y, Lopez JA, James DE, Hunziker W
The Journal of biological chemistry (2008) 2831: 324-31. 148 002 WB, ICC
The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.
Mistry AC, Mallick R, Fröhlich O, Klein JD, Rehm A, Chen G, Sands JM
The Journal of biological chemistry (2007) 28241: 30097-106. 148 002 WB, ICC; tested species: rabbit
The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release.
Krapivinsky G, Mochida S, Krapivinsky L, Cibulsky SM, Clapham DE
Neuron (2006) 523: 485-96. 148 002 WB
A novel role for snapin in dendrite patterning: interaction with cypin.
Chen M, Lucas KG, Akum BF, Balasingam G, Stawicki TM, Provost JM, Riefler GM, Jörnsten RJ, Firestein BL
Molecular biology of the cell (2005) 1611: 5103-14. 148 002 ICC, WB; tested species: rat
Cat. No.: 148 002
Amount: 200 µl
Price: $360.00