Synaptic Systems

Cat. No.: 148 002

Amount: 200 µl

Price: $360.00

Cat. No. 148 002	200 µl antiserum, lyophilized. For reconstitution add 200 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 100 up to 1 : 5000 IP: yes ICC: 1 : 500 gallery IHC: 1 : 500 gallery IHC-P: 1 : 500 gallery
Immunogen	Recombinant protein corresponding to AA 1 to 136 from rat Snapin (UniProt Id: P60192)
Reactivity	Reacts with: human (O95295), rat (P60192), mouse (Q9Z266), rabbit. No signal: zebrafish. Other species not tested yet.
Specificity	K.O. validated PubMed: 20946101
Matching control protein/peptide	148-0P
Remarks	Since snapin is present in very low concentrations long exposure time is recommended.
Data sheet	148_002.pdf

Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells.
Matsui T, Sakamaki Y, Nakashima S, Fukuda M
Cell reports (2022) 399: 110875. 148 002 WB; tested species: human

A Ragulator-BORC interaction controls lysosome positioning in response to amino acid availability.
Pu J, Keren-Kaplan T, Bonifacino JS
The Journal of cell biology (2017) 21612: 4183-4197. 148 002 WB; tested species: human

Dysbindin-associated proteome in the p2 synaptosome fraction of mouse brain.
Han MH, Hu Z, Chen CY, Chen Y, Gucek M, Li Z, Markey SP
Journal of proteome research (2014) 1311: 4567-80. 148 002 WB; tested species: mouse

LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25.
Yun HJ, Park J, Ho DH, Kim H, Kim CH, Oh H, Ga I, Seo H, Chang S, Son I, Seol W, et al.
Experimental & molecular medicine (2013) 45: e36. 148 002 IP, WB; tested species: mouse

Snapin deficiency is associated with developmental defects of the central nervous system.
Zhou B, Zhu YB, Lin L, Cai Q, Sheng ZH
Bioscience reports (2011) 312: 151-8. 148 002 WB; KO verified; tested species: mouse

The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells.
Ginter-Matuszewska B, Spik A, Rembiszewska A, Koyias C, Kupryjanczyk J, Jaruzelska J
Molecular human reproduction (2009) 153: 173-9. 148 002 WB, IHC-P; tested species: human,mouse

Snapin interacts with the Exo70 subunit of the exocyst and modulates GLUT4 trafficking.
Bao Y, Lopez JA, James DE, Hunziker W
The Journal of biological chemistry (2008) 2831: 324-31. 148 002 WB, ICC

The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.
Mistry AC, Mallick R, Fröhlich O, Klein JD, Rehm A, Chen G, Sands JM
The Journal of biological chemistry (2007) 28241: 30097-106. 148 002 WB, ICC; tested species: rabbit

The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release.
Krapivinsky G, Mochida S, Krapivinsky L, Cibulsky SM, Clapham DE
Neuron (2006) 523: 485-96. 148 002 WB

A novel role for snapin in dendrite patterning: interaction with cypin.
Chen M, Lucas KG, Akum BF, Balasingam G, Stawicki TM, Provost JM, Riefler GM, Jörnsten RJ, Firestein BL
Molecular biology of the cell (2005) 1611: 5103-14. 148 002 ICC, WB; tested species: rat

Cat. No.: 148 002

Amount: 200 µl

Price: $360.00

ICC

IHC

IHC-P

Background

Protocols

Snapin antibody - 148 002 K.O.