|Cat. No. 147 004||100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.|
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery
IP: not tested yet
ICC: not recommended
IHC: not recommended
IHC-P/FFPE: not tested yet
|Immunogen||Recombinant protein corresponding to AA 294 to 736 from rat Gephyrin (UniProt Id: Q03555)|
Reacts with: rat (Q03555), mouse (Q8BUV3).
Other species not tested yet.
|Specificity||Specific for gephyrin, detects all splice isoforms.|
|Matching control protein/peptide||147-1P|
|Remarks||This antibody gives better results in WB than the rabbit antibody.|
Gephyrin is a bifunctional protein which is essential for both synaptic clustering of inhibitory neurotransmitter receptors in the central nervous system and the biosynthesis of the molybdenum cofactor (MoCo) in peripheral tissues. It co-purifies with the inhibitory glycine receptor (GlyR) and is expressed abundantly in all brain areas which contain synapses.