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Bassoon - 141 016

A large multi-domain protein of the presynaptic active zone
Polyclonal chicken IgY fraction
Cat. No.: 141 016
Amount: 200 µl
Price: 350.00 €
Cat. No. 141 016 200 µl antibody, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Applications WB: not recommended
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to AA 756 to 1001 from rat Bassoon (UniProt Id: O88778)
Reactivity Reacts with: rat (O88778), mouse (O88737).
Other species not tested yet.
Specificity Specific for bassoon.
Data sheet 141_016.pdf

References for Bassoon - 141 016

Coherent Activity between the Prelimbic and Auditory Cortex in the Slow-Gamma Band Underlies Fear Discrimination.
Concina G, Cambiaghi M, Renna A, Sacchetti B
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3839: 8313-8328. 141 016 IHC; tested species: rat
Cat. No.: 141 016
Quantity: 200 µl
Price: 350.00 €
Coherent Activity between the Prelimbic and Auditory Cortex in the Slow-Gamma Band Underlies Fear Discrimination.
Concina G, Cambiaghi M, Renna A, Sacchetti B
The Journal of neuroscience : the official journal of the Society for Neuroscience (2018) 3839: 8313-8328. 141 016 IHC; tested species: rat
Background

Bassoon is a large protein which consists of an N-terminal Zn2+ finger and several piccolo-bassoon homology domains (PBH-domains). It is generally found together with piccolo, a related huge multi-domain protein of the CAZ (cytoskeletal matrix assembled at active zones).
Bassoon was suggested to be a scaffolding element of the presynapse but deletion experiments in mice have shown that bassoon is also involved in synaptic vesicle cycling. Probably bassoon interacts with other protein factors via its Zn2+ domain but the potential partners have not been determined yet.