Tailor-made Antibodies
and Tools for Life Science

RIM2 antibody - 140 303

RIMs are Rab3 effector proteins of the cytomatrix at the active zone
Rabbit polyclonal purified antibody
Cat. No.: 140 303
Amount: 50 µg
Price: $380.00
Cat. No. 140 303 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: not tested yet
IHC: 1 : 1000 gallery  
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 909 to 1076 from rat RIM2-4C (UniProt Id: Q9JIS1-3)
Reactivity Reacts with: rat (Q9JIS1), mouse (Q9EQZ7).
No signal: zebrafish.
Other species not tested yet.
Matching control protein/peptide 140-03P
Data sheet 140_303.pdf

References for RIM2 - 140 303

Loss of Function of RIMS2 Causes a Syndromic Congenital Cone-Rod Synaptic Disease with Neurodevelopmental and Pancreatic Involvement.
Mechaussier S, Almoallem B, Zeitz C, Van Schil K, Jeddawi L, Van Dorpe J, Dueñas Rey A, Condroyer C, Pelle O, Polak M, Boddaert N, et al.
American journal of human genetics (2020) : . 140 303 WB; tested species: human
Postsynaptic RIM1 modulates synaptic function by facilitating membrane delivery of recycling NMDARs in hippocampal neurons.
Wang J, Lv X, Wu Y, Xu T, Jiao M, Yang R, Li X, Chen M, Yan Y, Chen C, Dong W, et al.
Nature communications (2018) 91: 2267. 140 303 WB; tested species: mouse
Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.
Löhner M, Babai N, Müller T, Gierke K, Atorf J, Joachimsthaler A, Peukert A, Martens H, Feigenspan A, Kremers J, Schoch S, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 3733: 7848-7863. 140 303 WB, IHC; tested species: mouse
RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors.
Grabner CP, Gandini MA, Rehak R, Le Y, Zamponi GW, Schmitz F
The Journal of neuroscience : the official journal of the Society for Neuroscience (2015) 3538: 13133-47. 140 303 IHC, WB
Cat. No.: 140 303
Amount: 50 µg
Price: $380.00