Tailor-made Antibodies
and Tools for Life Science

VMaT2 antibody C-terminus - 138 302

VMaT2 is a monoamine transporter in the membrane of small synaptic vesicles
Rabbit polyclonal antiserum
Cat. No.: 138 302
Amount: 200 µl
Price: $360.00
Cat. No. 138 302 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 100 up to 1 : 1000 (AP staining) (see remarks) gallery  
IP: not tested yet
ICC: 1 : 1000 (see remarks) gallery  
IHC: 1 : 500 gallery  
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 496 to 515 from rat VMaT2 (UniProt Id: Q01827)
Reactivity Reacts with: rat (Q8BRU6).
Other species not tested yet.
Remarks

WB:  VMaT 2 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.
ICC: Requires brief fixation with 4 % PFA for 2 min and subsequent ice cold methanol fixation for 10 min.

Data sheet 138_302.pdf

References for VMaT2 - 138 302

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2.
Kreutzberger AJB, Kiessling V, Doyle CA, Schenk N, Upchurch CM, Elmer-Dixon M, Ward AE, Preobraschenski J, Hussein SS, Tomaka W, Seelheim P, et al.
eLife (2020) 9: . 138 302 WB; tested species: rat
Effects of sleep disruption on stress, nigrostriatal markers, and behavior in a chronic/progressive MPTP male mouse model of parkinsonism.
Xu M, Bohlen JK, Moore C, Nipper MA, Finn DA, Jones CE, Lim MM, Meshul CK
Journal of neuroscience research (2019) 9712: 1706-1719. 138 302 WB; tested species: mouse
Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain.
Dervola KS, Johansen EB, Walaas SI, Fonnum F
Neurotoxicology (2015) 50: 38-45. 138 302 WB
Amphetamine regulates NR2B expression in Go2α knockout mice and thereby sustains behavioral sensitization.
Brunk I, Sanchis-Segura C, Blex C, Perreau-Lenz S, Bilbao A, Spanagel R, Ahnert-Hilger G
Journal of neurochemistry (2010) 1151: 234-46. 138 302 WB; tested species: mouse
Chronic low-level lead exposure affects the monoaminergic system in the mouse superior olivary complex.
Fortune T, Lurie DI
The Journal of comparative neurology (2009) 5135: 542-58. 138 302 IHC, WB; tested species: mouse
Deletion of Go2alpha abolishes cocaine-induced behavioral sensitization by disturbing the striatal dopamine system.
Brunk I, Blex C, Sanchis-Segura C, Sternberg J, Perreau-Lenz S, Bilbao A, Hörtnagl H, Baron J, Juranek J, Laube G, Birnbaumer L, et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2008) 2210: 3736-46. 138 302 WB
The first luminal domain of vesicular monoamine transporters mediates G-protein-dependent regulation of transmitter uptake.
Brunk I, Blex C, Rachakonda S, Höltje M, Winter S, Pahner I, Walther DJ, Ahnert-Hilger G
The Journal of biological chemistry (2006) 28144: 33373-85. 138 302 WB, ICC
Cat. No.: 138 302
Amount: 200 µl
Price: $360.00