Cat. No.: 136-0P
Amount: 100 µg
Price:
$105.00
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| Cat. No. 136-0P |
100 µg protein, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in TBS. Then aliquot and store at -20°C to -80°C until use. Control proteins should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
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| Immunogen | Recombinant protein corresponding to AA 1 to 118 from rat VAMP4 (UniProt Id: D4A560) |
| Recommended dilution | Optimal concentrations should be determined by the end-user. |
| Remarks |
This control protein consists of the recombinant protein (aa 1 - 118 of rat VAMP 4) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of protein needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 136-0p.pdf |
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VAMP 4 belongs to the family of vesicle-associated membrane proteins and has a size of 16.5 kDa. It is involved in trans-Golgi network trafficking and and the maturation of secretory granules.
VAMP 4 co-immunoprecipitates with syntaxin 6, syntaxin 16, vti1a and vti1b. The highest expression levels are observed in brain but considerable amounts are also detectable in other tissues like heart, spleen and lung. In liver an additional splice variant of approximately 25 kDa has been described.