Tailor-made Antibodies
and Tools for Life Science
my list | quick order | cart
0
|
login
Home > Products > 135 307

VGLUT1 antibody - 135 307 K.O.

VGluT1 is a glutamate transporter in the membrane of synaptic vesicles
Goat polyclonal antiserum
Cat. No.: 135 307
Amount: 200 µl
Price: $335.00
Cat. No. 135 307 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) (see remarks) gallery  
IP: yes
ICC: 1 : 1000 up to 1 : 10000 gallery  
IHC: 1 : 300 gallery  
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to residues near the carboxy terminus of rat VGLUT 1 (UniProt Id: Q62634)
Reactivity Reacts with: rat (Q62634), mouse (Q3TXX4).
Other species not tested yet.
Specificity K.O. validated
Matching control protein/peptide 135-3P
Remarks

This antibody is highly recommended as a marker for glutamatergic nerve terminals.
WB:  VGLUT 1 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.
This antibody is highly recommended as marker for glutamatergic nerve terminals and gives excellent results in ICC.
Data sheet 135_307.pdf

References for VGLUT1 - 135 307

Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery.
Aiken J, Holzbaur ELF
Current biology : CB (2024) 348: 1687-1704.e8. 135 307 ICC; tested species: human
CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice.
Halperin D, Stavsky A, Kadir R, Drabkin M, Wormser O, Yogev Y, Dolgin V, Proskorovski-Ohayon R, Perez Y, Nudelman H, Stoler O, et al.
Nature communications (2021) 121: 6187. 135 307 ICC; tested species: mouse
Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation.
Stavsky A, Stoler O, Kostic M, Katoshevsky T, Assali EA, Savic I, Amitai Y, Prokisch H, Leiz S, Daumer-Haas C, Fleidervish I, et al.
Communications biology (2021) 41: 666. 135 307 ICC; tested species: mouse
PSD-95 promotes the stabilization of young synaptic contacts.
Taft CE, Turrigiano GG
Philosophical transactions of the Royal Society of London. Series B, Biological sciences (2014) 3691633: 20130134. 135 307 ICC; tested species: rat
Cat. No.: 135 307
Amount: 200 µl
Price: $335.00
WB
WB
ICC
IHC
Other products for this target