Synaptic Systems

Cat. No.: 135 011

Amount: 100 µg

Price: $425.00

Cat. No. 135 011	100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 up to 1 : 5000 (AP staining) (see remarks) gallery IP: yes ICC: 1 : 500 up to 1 : 1000 gallery IHC: 1 : 500 up to 1 : 1000 gallery IHC-P: 1 : 1000 gallery
Clone	68B7
Subtype	IgG1 (κ light chain)
Immunogen	Synthetic peptide corresponding to residues near the carboxy terminus of rat VGLUT 1 (UniProt Id: Q62634)
Reactivity	Reacts with: rat (Q62634), mouse (Q3TXX4). Other species not tested yet.
Specificity	K.O. validated
Matching control protein/peptide	135-0P
Remarks	WB: This antibody is highly recommended for Western blot experiments. VGLUT 1 aggregates after boiling, making it necessary to run SDS-PAGE with non-boiled samples.
Data sheet	135_011.pdf

The impact of exogenous Oxytocin on visual cortex plasticity across different stages of visual development.
Sun Y, Wang X, Chen Y, Luan Z, Hao R
Scientific reports (2025) 151: 12137. 135 011 WB, IHC; tested species: mouse

Monitoring of activity-driven trafficking of endogenous synaptic proteins through proximity labeling.
Pascual-Caro C, de Juan-Sanz J
PLoS biology (2024) 2210: e3002860. 135 011 WB; tested species: rat

VPS13A knockdown impairs corticostriatal synaptic plasticity and locomotor behavior in a new mouse model of chorea-acanthocytosis.
García-García E, Ramón-Lainez A, Conde-Berriozabal S, Del Toro D, Escaramis G, Giralt A, Masana M, Alberch J, Rodríguez MJ
Neurobiology of disease (2023) 187: 106292. 135 011 WB; tested species: mouse

Enriched environment attenuates hippocampal theta and gamma rhythms dysfunction in chronic cerebral hypoperfusion via improving imbalanced neural afferent levels.
Zheng J, Peng S, Cui L, Liu X, Li T, Zhao Z, Li Y, Hu Y, Zhang M, Xu L, Zhang J, et al.
Frontiers in cellular neuroscience (2023) 17: 985246. 135 011 WB; tested species: rat

Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3.
Upmanyu N, Jin J, Emde HV, Ganzella M, Bösche L, Malviya VN, Zhuleku E, Politi AZ, Ninov M, Silbern I, Leutenegger M, et al.
Neuron (2022) : . 135 011 WB, UPTAKE; tested species: rat

Maternal stress and vulnerability to depression: coping and maternal care strategies and its consequences on adolescent offspring.
Alves RL, Portugal CC, Lopes IM, Oliveira P, Alves CJ, Barbosa F, Summavielle T, Magalhães A
Translational psychiatry (2022) 121: 463. 135 011 WB; tested species: mouse

CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation.
Dong Z, Chen W, Chen C, Wang H, Cui W, Tan Z, Robinson H, Gao N, Luo B, Zhang L, Zhao K, et al.
Neuron (2020) 1053: 475-490.e6. 135 011 WB; tested species: mouse

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2.
Kreutzberger AJB, Kiessling V, Doyle CA, Schenk N, Upchurch CM, Elmer-Dixon M, Ward AE, Preobraschenski J, Hussein SS, Tomaka W, Seelheim P, et al.
eLife (2020) 9: . 135 011 WB; tested species: rat

Synaptic zinc contributes to motor and cognitive deficits in 6-hydroxydopamine mouse models of Parkinson's disease.
Sikora J, Kieffer BL, Paoletti P, Ouagazzal AM
Neurobiology of disease (2019) 134: 104681. 135 011 WB; tested species: mouse