Cat. No.: 129 204
Amount: 100 µl
Price:
$365.00
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| Cat. No. 129 204 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not recommended IHC: not recommended IHC-P: not tested yet |
| Immunogen | Synthetic peptide corresponding to AA 750 to 767 from rat Neuroligin2 (UniProt Id: Q62888) |
| Reactivity |
Reacts with: rat (Q62888), mouse (Q69ZK9). Other species not tested yet. |
| Specificity | K.O. validated |
| Data sheet | 129_204.pdf |
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Neuroligins form a family of postsynaptic cell surface molecules that interact with β-neurexins. They are 110-120 kDa polypeptides with homology to acetylcholine esterase. Neuroligin 1 and neuroligin 3 are specifically localized to post-synaptic densities of excitatory synapses whereas neuroligin 2 is found exclusively on inhibitory synapses.
Mutations in neuroligin 3 and neuroligin 4 have been implicated with a rare, heritable form of autism.