Tailor-made Antibodies
and Tools for Life Science

alpha/beta Synuclein antibody - 128 111

Synucleins are involved in Parkinson's and Alzheimer's Disease
Mouse monoclonal purified IgG
Cat. No.: 128 111
Amount: 100 µg
Price: $420.00
Cat. No. 128 111 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: yes (see remarks)
ICC: 1 : 500 gallery  
IHC: 1 : 200 up to 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Clone 56F2
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 140 from human α-Synuclein (UniProt Id: P37840)
Reactivity Reacts with: human (P37840, Q16143), rat (P37377, Q63754), mouse (O55042, Q91ZZ3).
Other species not tested yet.
Specificity Recognizes α- and β-synuclein.
Remarks

IP: Precipitates mainly β-synuclein.

Data sheet 128_111.pdf

References for alpha/beta Synuclein - 128 111

Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases.
Sambri I, D'Alessio R, Ezhova Y, Giuliano T, Sorrentino NC, Cacace V, De Risi M, Cataldi M, Annunziato L, De Leonibus E, Fraldi A, et al.
EMBO molecular medicine (2017) 91: 112-132. 128 111 ICC; tested species: mouse
Cat. No.: 128 111
Amount: 100 µg
Price: $420.00