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Home > Products > 124 214

SAP102 antibody - 124 214 K.O.

SAP102 is a component of postsynaptic densities
Guinea pig polyclonal antiserum
Cat. No.: 124 214
Amount: 100 µl
Price: $365.00
Cat. No. 124 214 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 100 up to 1 : 500 gallery  
IHC: not recommended
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 146 from mouse SAP102 (UniProt Id: P70175)
Reactivity Reacts with: rat (Q62936), mouse (P70175).
Other species not tested yet.
Specificity K.O. validated
Data sheet 124_214.pdf

References for SAP102 - 124 214

Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal.
Grochowska KM, Sperveslage M, Raman R, Failla AV, Głów D, Schulze C, Laprell L, Fehse B, Kreutz MR
Cell reports (2023) 428: 112998. 124 214 ICC; tested species: rat
Cat. No.: 124 214
Amount: 100 µl
Price: $365.00
Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal.
Grochowska KM, Sperveslage M, Raman R, Failla AV, Głów D, Schulze C, Laprell L, Fehse B, Kreutz MR
Cell reports (2023) 428: 112998. 124 214 ICC; tested species: rat
WB
WB
ICC
Background

SAP 102 (synapse associated protein of 102 kDa, also called DLG 3) belongs to the PSD 95 family containing a modular structure with three PDZ-, one SH3- and a guanylate kinase-like domain. It is a component of postsynaptic densities in central synapses. It is involved in NMDA receptor clustering and immobilization. In vitro, all three PDZ domains in SAP 102 bind the cytoplasmic tail of NR2B.
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