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Home > Products > 116 003

Munc18-1 antibody - 116 003 K.D.

Munc18 proteins are peripheral membrane protein involved in vesicle docking and fusion
Rabbit polyclonal purified antibody
Cat. No.: 116 003
Amount: 50 µg
Price: $460.00
Cat. No. 116 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
DNA-PAINT: yes (see remarks)
Immunogen Synthetic peptide corresponding to AA 580 to 594 from rat Munc18-1 (UniProt Id: P61765)
Reactivity Reacts with: human (P61764), rat (P61765), mouse (O08599), cow.
Other species not tested yet.
Specificity K.D. validated PubMed: 34103363
Matching control protein/peptide 116-0P
Remarks

DNA-PAINT: This antibody has been successfully used for DNA-PAINT application (see Unterauer et al., 2024; PMID: 38552614).
Data sheet 116_003.pdf

References for Munc18-1 - 116 003

Expression of synaptic proteins and development of dendritic spines in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa.
Sobierajski E, Czubay K, Schmidt MR, Wiedenski S, Rettschlag S, Beemelmans C, Beemelmans C, Wahle P
Brain structure & function (2025) 2302: 38. 116 003 WB; tested species: pig
Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.
Farsi Z, Nicolella A, Simmons SK, Aryal S, Shepard N, Brenner K, Lin S, Herzog L, Moran SP, Stalnaker KJ, Shin W, et al.
Neuron (2023) 11121: 3378-3396.e9. 116 003 WB; tested species: mouse
Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity.
Barber CN, Goldschmidt HL, Ma Q, Devine LR, Cole RN, Huganir RL, Raben DM
Frontiers in synaptic neuroscience (2022) 14: 855673. 116 003 WB; tested species: rat
Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors.
Pronot M, Poupon G, Pizzamiglio L, Prieto M, Chato-Astrain I, Lacagne I, Schorova L, Folci A, Brau F, Martin S
Cellular and molecular life sciences : CMLS (2022) 797: 378. 116 003 WB; tested species: rat
Munc18-1 is essential for neuropeptide secretion in neurons.
Puntman DC, Arora S, Farina M, Toonen RF, Verhage M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2021) : . 116 003 WB; KD verified; tested species: mouse
Cat. No.: 116 003
Amount: 50 µg
Price: $460.00
WB
ICC
IHC
IHC-P
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