Tailor-made Antibodies
and Tools for Life Science

Dynamin1/2/3 antibody - 115 002 K.D.

Dynamins are GTPases involved in endocytosis
Rabbit polyclonal antiserum
Cat. No.: 115 002
Amount: 200 µl
Price: $360.00
Cat. No. 115 002 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 200 up to 1 : 1000 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 100 gallery  
Immunogen Synthetic peptide corresponding to AA 2 to 17 from rat Dynamin1 (UniProt Id: P21575)
Reactivity Reacts with: human (Q05193, P50570, Q9UQ16), rat (P21575, P39052, Q08877), mouse (P39053, P39054, Q8BZ98), cow.
Other species not tested yet.
Specificity Recognizes dynamin 1, 2 and 3 with a preference for dynamin 1. K.D. validated PubMed: 32989096
Matching control protein/peptide 115-0P
Data sheet 115_002.pdf

References for Dynamin1/2/3 - 115 002

Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission.
Liu GT, Kochlamazashvili G, Puchkov D, Müller R, Schultz C, Mackintosh AI, Vollweiter D, Haucke V, Soykan T
The EMBO journal (2022) : e109352. 115 002 WB; tested species: rat
Release mode dynamically regulates the RRP refilling mechanism at individual hippocampal synapses.
Kim Y, Lee U, Choi C, Chang S
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) : . 115 002 WB, ICC; KD verified; tested species: rat
VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context.
Richter K, Schmutz I, Darna M, Zander JF, Chavan R, Albrecht U, Ahnert-Hilger G
Neuroscience (2018) 371: 29-37. 115 002 WB; tested species: mouse
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting.
Biesemann C, Grønborg M, Luquet E, Wichert SP, Bernard V, Bungers SR, Cooper B, Varoqueaux F, Li L, Byrne JA, Urlaub H, et al.
The EMBO journal (2014) 332: 157-70. 115 002 WB; tested species: mouse
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 115 002 WB
Small-scale isolation of synaptic vesicles from mammalian brain.
Ahmed S, Holt M, Riedel D, Jahn R
Nature protocols (2013) 85: 998-1009. 115 002 WB; tested species: mouse
Efficient synaptic vesicle recycling after intense exocytosis concomitant with the accumulation of non-releasable endosomes at early developmental stages.
Bartolomé-Martín D, Ramírez-Franco J, Castro E, Sánchez-Prieto J, Torres M
Journal of cell science (2012) 125Pt 2: 422-34. 115 002 WB, ICC; tested species: rat
Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease.
Rozas JL, Gómez-Sánchez L, Tomás-Zapico C, Lucas JJ, Fernández-Chacón R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 313: 1106-13. 115 002 WB
Dynamic interaction of amphiphysin with N-WASP regulates actin assembly.
Yamada H, Padilla-Parra S, Park SJ, Itoh T, Chaineau M, Monaldi I, Cremona O, Benfenati F, De Camilli P, Coppey-Moisan M, Tramier M, et al.
The Journal of biological chemistry (2009) 28449: 34244-56. 115 002 WB
Molecular anatomy of a trafficking organelle.
Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, et al.
Cell (2006) 1274: 831-46. 115 002 WB
Cat. No.: 115 002
Amount: 200 µl
Price: $360.00