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Clathrin light chain - 113 004

Small clathrin coat subunits involved in endocytosis
Polyclonal Guinea pig antiserum
Cat. No.: 113 004
Amount: 100 µl
Price: 350.00 €
Cat. No. 113 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Applications WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P/FFPE: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 156 to 173 from rat Clathrin light chainB (UniProt Id: P08082)
Reactivity Reacts with: rat, mouse.
Other species not tested yet.
Specificity Specific for both neuronal light chains, does not cross-react with the non-neuronal variants.
Matching control protein/peptide 113-0P
Data sheet 113_004.pdf
Cat. No.: 113 004
Quantity: 100 µl
Price: 350.00 €
Background
Clathrin consists of heavy chains and light chains that co-assemble to triskelions. The light chains are differentially spliced, with neurons expressing a special variant that is not detectable elsewhere. The neuron-specific light chains are enriched in synaptic nerve terminals where they participate in synaptic vesicle endocytosis.