|Cat. No. 112 303||50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.|
WB: 1 : 500 up to 1 : 2000 (AP staining) gallery
ICC: not tested yet
IHC: not tested yet
IHC-P/FFPE: not tested yet
|Immunogen||Synthetic peptide corresponding to AA 2 to 18 from rat γSNAP (UniProt Id: Q9CWZ7)|
Reacts with: human (Q99747), rat, mouse (Q9CWZ7), cow.
No signal: zebrafish.
Other species not tested yet.
|Specificity||Specific for γ SNAP.|
|Matching control protein/peptide||112-3P|
The proteins α/β-SNAP are two related soluble and highly conserved proteins that bind to the fusion complex (SNARE complex), thus allowing the N-ethylmaleimide sensitive fusion protein NSF to bind to the complex. γ-SNAP binds directly to NSF and Gaf-1/Rip11, a protein of the Rab11 interacting family. In contrast to α/β-SNAP it does not interact directly with SNARE proteins and is not required for ER-Golgi transport. SNAP-proteins are abundantly expressed in all tissues. They are partially soluble, partially membrane-bound.