|Cat. No. 110 113||50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.|
WB: 1 : 1000 (AP staining) gallery
ICC: 1 : 100 gallery
IHC: not tested yet
IHC-P/FFPE: 1 : 500 gallery
|Immunogen||Synthetic peptide corresponding to AA 1 to 15 from mouse Syntaxin11 (UniProt Id: Q9D3G5)|
Reacts with: rat (A0A0G2K516), mouse (Q9D3G5), human (O75558).
Other species not tested yet.
|Specificity||Specific for syntaxin 11, no cross reactivity to other syntaxins. K.O.|
|Matching control protein/peptide||110-11P|
Syntaxin 11, a member of the SNARE family of proteins, localizes to late endosomes and the trans-Golgi network and has been shown to interact with VAMP proteins and SNAP 23. Unlike other syntaxins it does not possess a carboxy-terminal transmembrane anchor.
In the immune systems several cell types like phagocytic immune cells, resting natural killer (NK) cells and CD8-T-cells express syntaxin 11. High levels of protein can also be found in lung and placenta but not in brain where it is almost undetectable.