Synaptic Systems - Syntaxin4

Cat. No.: 110 043

Amount: 50 µg

Price: $460.00

Cat. No. 110 043	50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery IP: yes ICC: 1 : 100 up to 1 : 500 gallery IHC: not tested yet IHC-P: not tested yet EM: yes
Immunogen	Recombinant protein corresponding to AA 1 to 273 from rat Syntaxin4 (UniProt Id: Q08850)
Reactivity	Reacts with: human (Q12846), rat (Q08850), mouse (P70452), hamster. Other species not tested yet.
Specificity	K.D. validated PubMed: 31128202
Matching control protein/peptide	110-4P
Data sheet	110_043.pdf

Microglia modulate gliotransmission through the regulation of VAMP2 proteins in astrocytes.
Takata-Tsuji F, Chounlamountri N, Do LD, Philippot C, Novion Ducassou J, Couté Y, Ben Achour S, Honnorat J, Place C, Pascual O
Glia (2021) 691: 61-72. 110 043 WB; tested species: mouse

Melanophilin Accelerates Insulin Granule Fusion Without Predocking to the Plasma Membrane.
Wang H, Mizuno K, Takahashi N, Kobayashi E, Shirakawa J, Terauchi Y, Kasai H, Okunishi K, Izumi T
Diabetes (2020) : . 110 043 WB, IP, ICC; tested species: mouse

SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.
Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, et al.
JCI insight (2020) 53: . 110 043 WB; tested species: human,mouse

Role of SNAREs in the Atopic Dermatitis-related Cytokine Secretion and Skin-Nerve Communication.
Meng J, Wang J, Buddenkotte J, Buhl T, Steinhoff M
The Journal of investigative dermatology (2019) : . 110 043 WB; KD verified; tested species: human

Syntaxin 4 is concentrated on plasma membrane of astrocytes.
Tao-Cheng JH, Pham A, Yang Y, Winters CA, Gallant PE, Reese TS
Neuroscience (2015) 286: 264-71. 110 043 WB, EM

Blockade of the SNARE protein syntaxin 1 inhibits glioblastoma tumor growth.
Ulloa F, Gonzàlez-Juncà A, Meffre D, Barrecheguren PJ, Martínez-Mármol R, Pazos I, Olivé N, Cotrufo T, Seoane J, Soriano E
PloS one (2015) 103: e0119707. 110 043 WB

The major myelin-resident protein PLP is transported to myelin membranes via a transcytotic mechanism: involvement of sulfatide.
Baron W, Ozgen H, Klunder B, de Jonge JC, Nomden A, Plat A, Trifilieff E, de Vries H, Hoekstra D
Molecular and cellular biology (2015) 351: 288-302. 110 043 WB

Cat. No.: 110 043

Amount: 50 µg

Price: $460.00

ICC

Background

Protocols

Syntaxin4 antibody - 110 043 K.D.