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Rab 5 peptide - 108-0P

Rab5 is a GTP-binding protein involved in endocytosis
control peptide
Cat. No.: 108-0P
Amount: 100 µg
Price: $90.00
Cat. No. 108-0P 100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Control peptides should be stored at -20°C when still lyophilized!
Immunogen Synthetic peptide corresponding to AA 192 to 196 from mouse Rab5 (UniProt Id: Q9CQD1)
Recommended dilution Optimal concentrations should be determined by the end-user.
Matching antibodies 108 002
Remarks

This control peptide consists of the synthetic peptide (aa 182-196 in mouse rab 5) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.

Data sheet 108-0p.pdf
Cat. No.: 108-0P
Quantity: 100 µg
Price: $90.00
Background
Rab 5 is a member of the Rab protein family that belongs to the ras-related superfamily of small monomeric GTPases. Rab 5 is ubiquitously expressed in all tissues where it functions in the fusion of early endosomes which is the first fusion step of endocytic organelles after their formation and detachment from the plasma membrane. It is presently the best marker with selectivity for this compartment.
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