Rab5 peptide - 108-0P

Rab5 is a GTP-binding protein involved in endocytosis

control peptide

Cat. No.: 108-0P

Amount: 100 µg

Price: $110.00

Cat. No. 108-0P	100 µg peptide, lyophilized. For reconstitution add 100 µl H₂O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized!
Applications
Immunogen	Synthetic peptide corresponding to AA 192 to 196 from mouse Rab5 (UniProt Id: Q9CQD1)
Recommended dilution	Optimal concentrations should be determined by the end-user.
Matching antibodies	108 002
Remarks	This control peptide consists of the synthetic peptide (aa 182-196 in mouse rab 5) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen.
Data sheet	Datasheet 108-0p

Cat. No.: 108-0P

Amount: 100 µg

Price: $110.00

Background

Rab 5 is a member of the Rab protein family that belongs to the ras-related superfamily of small monomeric GTPases. Rab 5 is ubiquitously expressed in all tissues where it functions in the fusion of early endosomes which is the first fusion step of endocytic organelles after their formation and detachment from the plasma membrane. It is presently the best marker with selectivity for this compartment.

1 ) Somsel Rodman J et al., J. Cell. Sci. (2000)
2 ) Ikin AF et al., J. Biol. Chem. (1996)

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