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Cellubrevin - 104 103

Major vesicle protein involved in fusion
Polyclonal rabbit purified antibody
Cat. No.: 104 103
Amount: 50 µg
Price: $450.00
Cat. No. 104 103 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Applications WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: yes
ICC: yes
IHC: yes
IHC-P/FFPE: 1 : 200 gallery  
EM: yes
Immunogen Synthetic peptide corresponding to AA 2 to 14 from rat Cellubrevin (UniProt Id: P63025)
Reactivity Reacts with: rat (P63025), mouse (P63024), pig.
No signal: human, zebrafish.
Other species not tested yet.
Specificity Specific for VAMP 3. No cross reactivity to VAMP 1 and VAMP 2. K.O. PubMed: 25864578
Matching control protein/peptide 104-1P
Data sheet 104_103.pdf

References for Cellubrevin - 104 103

Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface.
Shipley FB, Dani N, Xu H, Deister C, Cui J, Head JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, et al.
Neuron (2020) 1084: 623-639.e10. 104 103 WB, IHC; tested species: mouse
Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes.
Morris S, Geoghegan ND, Sadler JBA, Koester AM, Black HL, Laub M, Miller L, Heffernan L, Simpson JC, Mastick CC, Cooper J, et al.
PeerJ (2020) 8: e8751. 104 103 WB; tested species: mouse
Cardiac SNARE Expression in Health and Disease.
Bowman PRT, Smith GL, Gould GW
Frontiers in endocrinology (2019) 10: 881. 104 103 WB; tested species: mouse
Invasion by activated macrophages requires delivery of nascent MT1-MMP through late endosomes/lysosomes to the cell surface.
Röhl J, West ZE, Rudolph M, Zaharia A, Van Lonkhuyzen D, Hickey DK, Semmler ABT, Murray RZ
Traffic (Copenhagen, Denmark) (2019) : . 104 103 WB; KD verified; tested species: mouse
Synaptotagmin-11 inhibits cytokine secretion and phagocytosis in microglia.
Du C, Wang Y, Zhang F, Yan S, Guan Y, Gong X, Zhang T, Cui X, Wang X, Zhang CX
Glia (2017) 6510: 1656-1667. 104 103 WB, ICC; tested species: mouse
Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.
García-Melero A, Reverter M, Hoque M, Meneses-Salas E, Koese M, Conway JR, Johnsen CH, Alvarez-Guaita A, Morales-Paytuvi F, Elmaghrabi YA, Pol A, et al.
The Journal of biological chemistry (2016) 2913: 1320-35. 104 103 WB, ICC
Characterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking.
Sadler JB, Bryant NJ, Gould GW
Molecular biology of the cell (2015) 263: 530-6. 104 103 WB
Vesicular transport system in myotubes: ultrastructural study and signposting with vesicle-associated membrane proteins.
Tajika Y, Takahashi M, Khairani AF, Ueno H, Murakami T, Yorifuji H
Histochemistry and cell biology (2014) 1414: 441-54. 104 103 WB, ICC; tested species: mouse
Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45.
Roccisana J, Sadler JB, Bryant NJ, Gould GW
Molecular biology of the cell (2013) 2415: 2389-97. 104 103 WB
Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cells.
Mendez M, Gross KW, Glenn ST, Garvin JL, Carretero OA
The Journal of biological chemistry (2011) 28632: 28608-18. 104 103 WB, ICC
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7.
Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5659-72. 104 103 WB, ICC, EM
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 104 103 WB
Molecular anatomy of the hair cell's ribbon synapse.
Uthaiah RC, Hudspeth AJ
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 3037: 12387-99. 104 103 WB
How pig sperm prepares to fertilize: stable acrosome docking to the plasma membrane.
Tsai PS, Garcia-Gil N, van Haeften T, Gadella BM
PloS one (2010) 56: e11204. 104 103 WB, IP; tested species: pig
Sunday driver interacts with two distinct classes of axonal organelles.
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V
The Journal of biological chemistry (2009) 28450: 34628-39. 104 103 WB, IP, IHC
VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways.
Tiwari N, Wang CC, Brochetta C, Ke G, Vita F, Qi Z, Rivera J, Soranzo MR, Zabucchi G, Hong W, Blank U, et al.
Blood (2008) 1117: 3665-74. 104 103 WB
Vesicle-associated membrane protein-8/endobrevin negatively regulates phagocytosis of bacteria in dendritic cells.
Ho YH, Cai DT, Wang CC, Huang D, Wong SH
Journal of immunology (Baltimore, Md. : 1950) (2008) 1805: 3148-57. 104 103 WB, ICC
How pig sperm prepares to fertilize: stable acrosome docking to the plasma membrane.
Tsai PS, Garcia-Gil N, van Haeften T, Gadella BM
PloS one (2010) 56: e11204. 104 103 WB, IP; tested species: pig
Sunday driver interacts with two distinct classes of axonal organelles.
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V
The Journal of biological chemistry (2009) 28450: 34628-39. 104 103 WB, IP, IHC
Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release.
Dhara M, Mantero Martinez M, Makke M, Schwarz Y, Mohrmann R, Bruns D
eLife (2020) 9: . 104 103 ICC; tested species: mouse
The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole.
Arango Duque G, Jardim A, Gagnon É, Fukuda M, Descoteaux A
PLoS pathogens (2019) 157: e1007982. 104 103 ICC; tested species: mouse
β1-integrin- and KV1.3 channel-dependent signaling stimulates glutamate release from Th17 cells.
Birkner K, Wasser B, Ruck T, Thalman C, Luchtman D, Pape K, Schmaul S, Bitar L, Krämer-Albers EM, Stroh A, Meuth SG, et al.
The Journal of clinical investigation (2019) : . 104 103 ICC; tested species: mouse
The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome.
Hayashi K, Taura M, Iwasaki A
Science signaling (2018) 11528: . 104 103 ICC; tested species: mouse
Synaptotagmin-11 inhibits cytokine secretion and phagocytosis in microglia.
Du C, Wang Y, Zhang F, Yan S, Guan Y, Gong X, Zhang T, Cui X, Wang X, Zhang CX
Glia (2017) 6510: 1656-1667. 104 103 WB, ICC; tested species: mouse
Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.
García-Melero A, Reverter M, Hoque M, Meneses-Salas E, Koese M, Conway JR, Johnsen CH, Alvarez-Guaita A, Morales-Paytuvi F, Elmaghrabi YA, Pol A, et al.
The Journal of biological chemistry (2016) 2913: 1320-35. 104 103 WB, ICC
Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity.
Hayashi K, Sasai M, Iwasaki A
International immunology (2015) 279: 435-45. 104 103 ICC
Astrocyte VAMP3 vesicles undergo Ca2+ -independent cycling and modulate glutamate transporter trafficking.
Li D, Hérault K, Zylbersztejn K, Lauterbach MA, Guillon M, Oheim M, Ropert N
The Journal of physiology (2015) 59313: 2807-32. 104 103 ICC; KO verified
Transcriptional expression of myelin basic protein in oligodendrocytes depends on functional syntaxin 4: a potential correlation with autocrine signaling.
Bijlard M, Klunder B, de Jonge JC, Nomden A, Tyagi S, de Vries H, Hoekstra D, Baron W
Molecular and cellular biology (2015) 354: 675-87. 104 103 ICC
Vesicular transport system in myotubes: ultrastructural study and signposting with vesicle-associated membrane proteins.
Tajika Y, Takahashi M, Khairani AF, Ueno H, Murakami T, Yorifuji H
Histochemistry and cell biology (2014) 1414: 441-54. 104 103 WB, ICC; tested species: mouse
Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation.
Yamazaki Y, Schönherr C, Varshney GK, Dogru M, Hallberg B, Palmer RH
The EMBO journal (2013) 324: 524-37. 104 103 ICC; tested species: human
SNARE protein expression and localization in human cytotoxic T lymphocytes.
Pattu V, Qu B, Schwarz EC, Strauss B, Weins L, Bhat SS, Halimani M, Marshall M, Rettig J, Hoth M
European journal of immunology (2012) 422: 470-5. 104 103 ICC
Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cells.
Mendez M, Gross KW, Glenn ST, Garvin JL, Carretero OA
The Journal of biological chemistry (2011) 28632: 28608-18. 104 103 WB, ICC
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7.
Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5659-72. 104 103 WB, ICC, EM
Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3.
Sasai M, Linehan MM, Iwasaki A
Science (New York, N.Y.) (2010) 3295998: 1530-4. 104 103 ICC
Vesicle-associated membrane protein-8/endobrevin negatively regulates phagocytosis of bacteria in dendritic cells.
Ho YH, Cai DT, Wang CC, Huang D, Wong SH
Journal of immunology (Baltimore, Md. : 1950) (2008) 1805: 3148-57. 104 103 WB, ICC
Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface.
Shipley FB, Dani N, Xu H, Deister C, Cui J, Head JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, et al.
Neuron (2020) 1084: 623-639.e10. 104 103 WB, IHC; tested species: mouse
Evidence for glutamate as a neuroglial transmitter within sensory ganglia.
Kung LH, Gong K, Adedoyin M, Ng J, Bhargava A, Ohara PT, Jasmin L
PloS one (2013) 87: e68312. 104 103 IHC
Sunday driver interacts with two distinct classes of axonal organelles.
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V
The Journal of biological chemistry (2009) 28450: 34628-39. 104 103 WB, IP, IHC
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7.
Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5659-72. 104 103 WB, ICC, EM
Cat. No.: 104 103
Quantity: 50 µg
Price: $450.00
Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface.
Shipley FB, Dani N, Xu H, Deister C, Cui J, Head JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, et al.
Neuron (2020) 1084: 623-639.e10. 104 103 WB, IHC; tested species: mouse
Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes.
Morris S, Geoghegan ND, Sadler JBA, Koester AM, Black HL, Laub M, Miller L, Heffernan L, Simpson JC, Mastick CC, Cooper J, et al.
PeerJ (2020) 8: e8751. 104 103 WB; tested species: mouse
Cardiac SNARE Expression in Health and Disease.
Bowman PRT, Smith GL, Gould GW
Frontiers in endocrinology (2019) 10: 881. 104 103 WB; tested species: mouse
Invasion by activated macrophages requires delivery of nascent MT1-MMP through late endosomes/lysosomes to the cell surface.
Röhl J, West ZE, Rudolph M, Zaharia A, Van Lonkhuyzen D, Hickey DK, Semmler ABT, Murray RZ
Traffic (Copenhagen, Denmark) (2019) : . 104 103 WB; KD verified; tested species: mouse
Synaptotagmin-11 inhibits cytokine secretion and phagocytosis in microglia.
Du C, Wang Y, Zhang F, Yan S, Guan Y, Gong X, Zhang T, Cui X, Wang X, Zhang CX
Glia (2017) 6510: 1656-1667. 104 103 WB, ICC; tested species: mouse
Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.
García-Melero A, Reverter M, Hoque M, Meneses-Salas E, Koese M, Conway JR, Johnsen CH, Alvarez-Guaita A, Morales-Paytuvi F, Elmaghrabi YA, Pol A, et al.
The Journal of biological chemistry (2016) 2913: 1320-35. 104 103 WB, ICC
Characterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking.
Sadler JB, Bryant NJ, Gould GW
Molecular biology of the cell (2015) 263: 530-6. 104 103 WB
Vesicular transport system in myotubes: ultrastructural study and signposting with vesicle-associated membrane proteins.
Tajika Y, Takahashi M, Khairani AF, Ueno H, Murakami T, Yorifuji H
Histochemistry and cell biology (2014) 1414: 441-54. 104 103 WB, ICC; tested species: mouse
Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45.
Roccisana J, Sadler JB, Bryant NJ, Gould GW
Molecular biology of the cell (2013) 2415: 2389-97. 104 103 WB
Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cells.
Mendez M, Gross KW, Glenn ST, Garvin JL, Carretero OA
The Journal of biological chemistry (2011) 28632: 28608-18. 104 103 WB, ICC
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7.
Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5659-72. 104 103 WB, ICC, EM
Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages.
Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL, Murray RZ
Traffic (Copenhagen, Denmark) (2011) 126: 762-73. 104 103 WB
Molecular anatomy of the hair cell's ribbon synapse.
Uthaiah RC, Hudspeth AJ
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 3037: 12387-99. 104 103 WB
How pig sperm prepares to fertilize: stable acrosome docking to the plasma membrane.
Tsai PS, Garcia-Gil N, van Haeften T, Gadella BM
PloS one (2010) 56: e11204. 104 103 WB, IP; tested species: pig
Sunday driver interacts with two distinct classes of axonal organelles.
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V
The Journal of biological chemistry (2009) 28450: 34628-39. 104 103 WB, IP, IHC
VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways.
Tiwari N, Wang CC, Brochetta C, Ke G, Vita F, Qi Z, Rivera J, Soranzo MR, Zabucchi G, Hong W, Blank U, et al.
Blood (2008) 1117: 3665-74. 104 103 WB
Vesicle-associated membrane protein-8/endobrevin negatively regulates phagocytosis of bacteria in dendritic cells.
Ho YH, Cai DT, Wang CC, Huang D, Wong SH
Journal of immunology (Baltimore, Md. : 1950) (2008) 1805: 3148-57. 104 103 WB, ICC
How pig sperm prepares to fertilize: stable acrosome docking to the plasma membrane.
Tsai PS, Garcia-Gil N, van Haeften T, Gadella BM
PloS one (2010) 56: e11204. 104 103 WB, IP; tested species: pig
Sunday driver interacts with two distinct classes of axonal organelles.
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V
The Journal of biological chemistry (2009) 28450: 34628-39. 104 103 WB, IP, IHC
Synergistic actions of v-SNARE transmembrane domains and membrane-curvature modifying lipids in neurotransmitter release.
Dhara M, Mantero Martinez M, Makke M, Schwarz Y, Mohrmann R, Bruns D
eLife (2020) 9: . 104 103 ICC; tested species: mouse
The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole.
Arango Duque G, Jardim A, Gagnon É, Fukuda M, Descoteaux A
PLoS pathogens (2019) 157: e1007982. 104 103 ICC; tested species: mouse
β1-integrin- and KV1.3 channel-dependent signaling stimulates glutamate release from Th17 cells.
Birkner K, Wasser B, Ruck T, Thalman C, Luchtman D, Pape K, Schmaul S, Bitar L, Krämer-Albers EM, Stroh A, Meuth SG, et al.
The Journal of clinical investigation (2019) : . 104 103 ICC; tested species: mouse
The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome.
Hayashi K, Taura M, Iwasaki A
Science signaling (2018) 11528: . 104 103 ICC; tested species: mouse
Synaptotagmin-11 inhibits cytokine secretion and phagocytosis in microglia.
Du C, Wang Y, Zhang F, Yan S, Guan Y, Gong X, Zhang T, Cui X, Wang X, Zhang CX
Glia (2017) 6510: 1656-1667. 104 103 WB, ICC; tested species: mouse
Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.
García-Melero A, Reverter M, Hoque M, Meneses-Salas E, Koese M, Conway JR, Johnsen CH, Alvarez-Guaita A, Morales-Paytuvi F, Elmaghrabi YA, Pol A, et al.
The Journal of biological chemistry (2016) 2913: 1320-35. 104 103 WB, ICC
Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity.
Hayashi K, Sasai M, Iwasaki A
International immunology (2015) 279: 435-45. 104 103 ICC
Astrocyte VAMP3 vesicles undergo Ca2+ -independent cycling and modulate glutamate transporter trafficking.
Li D, Hérault K, Zylbersztejn K, Lauterbach MA, Guillon M, Oheim M, Ropert N
The Journal of physiology (2015) 59313: 2807-32. 104 103 ICC; KO verified
Transcriptional expression of myelin basic protein in oligodendrocytes depends on functional syntaxin 4: a potential correlation with autocrine signaling.
Bijlard M, Klunder B, de Jonge JC, Nomden A, Tyagi S, de Vries H, Hoekstra D, Baron W
Molecular and cellular biology (2015) 354: 675-87. 104 103 ICC
Vesicular transport system in myotubes: ultrastructural study and signposting with vesicle-associated membrane proteins.
Tajika Y, Takahashi M, Khairani AF, Ueno H, Murakami T, Yorifuji H
Histochemistry and cell biology (2014) 1414: 441-54. 104 103 WB, ICC; tested species: mouse
Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation.
Yamazaki Y, Schönherr C, Varshney GK, Dogru M, Hallberg B, Palmer RH
The EMBO journal (2013) 324: 524-37. 104 103 ICC; tested species: human
SNARE protein expression and localization in human cytotoxic T lymphocytes.
Pattu V, Qu B, Schwarz EC, Strauss B, Weins L, Bhat SS, Halimani M, Marshall M, Rettig J, Hoth M
European journal of immunology (2012) 422: 470-5. 104 103 ICC
Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cells.
Mendez M, Gross KW, Glenn ST, Garvin JL, Carretero OA
The Journal of biological chemistry (2011) 28632: 28608-18. 104 103 WB, ICC
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7.
Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5659-72. 104 103 WB, ICC, EM
Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3.
Sasai M, Linehan MM, Iwasaki A
Science (New York, N.Y.) (2010) 3295998: 1530-4. 104 103 ICC
Vesicle-associated membrane protein-8/endobrevin negatively regulates phagocytosis of bacteria in dendritic cells.
Ho YH, Cai DT, Wang CC, Huang D, Wong SH
Journal of immunology (Baltimore, Md. : 1950) (2008) 1805: 3148-57. 104 103 WB, ICC
Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface.
Shipley FB, Dani N, Xu H, Deister C, Cui J, Head JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, et al.
Neuron (2020) 1084: 623-639.e10. 104 103 WB, IHC; tested species: mouse
Evidence for glutamate as a neuroglial transmitter within sensory ganglia.
Kung LH, Gong K, Adedoyin M, Ng J, Bhargava A, Ohara PT, Jasmin L
PloS one (2013) 87: e68312. 104 103 IHC
Sunday driver interacts with two distinct classes of axonal organelles.
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V
The Journal of biological chemistry (2009) 28450: 34628-39. 104 103 WB, IP, IHC
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7.
Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2011) 3115: 5659-72. 104 103 WB, ICC, EM
Background

Cellubrevin/VAMP3 is the non-neuronal isoform of the synaptobrevin/VAMP family which belongs to the v-SNAREs. Like the neuronal isoforms Synaptobrevin1/VAMP1 and Synaptobrevin2/VAMP2 it is composed of an N-terminal cytoplasmic region and a C-terminal transmembrane domain.
Cellubrevin/VAMP3 localizes to an endosomal membrane pool, where it constitutes an essential component of the membrane fusion machinery. Like the synaptobrevins, cellubrevin is a substrate for the tetanus toxin.