Synaptic Systems - Synaptogyrin1

Cat. No.: 103 002

Amount: 200 µl

Price: $360.00

Cat. No. 103 002	200 µl antiserum, lyophilized. For reconstitution add 200 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery IP: yes ICC: 1 : 500 up to 1 : 1000 gallery IHC: 1 : 200 gallery IHC-P: 1 : 500 gallery ELISA: yes (see remarks)
Immunogen	Synthetic peptide corresponding to AA 220 to 234 from rat Synaptogyrin1 (UniProt Id: Q62876)
Reactivity	Reacts with: human (O43759), rat (Q62876), mouse (O55100), hamster, chicken. No signal: zebrafish. Other species not tested yet.
Specificity	K.O. validated PubMed: 31090538
Matching control protein/peptide	103-0P
Remarks	ELISA: Suitable as detector antibody for sandwich-ELISA with cat. no. 103 011 as capture antibody. The ELISA-protocol for membrane proteins is recommended.
Data sheet	103_002.pdf

Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Wang C, Jiang W, Leitz J, Yang K, Esquivies L, Wang X, Shen X, Held RG, Adams DJ, Basta T, Hampton L, et al.
Nature (2024) 6318022: 899-904. 103 002 WB; tested species: mouse

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence.
Choi I, Wang M, Yoo S, Xu P, Seegobin SP, Li X, Han X, Wang Q, Peng J, Zhang B, Yue Z, et al.
Nature cell biology (2023) 257: 963-974. 103 002 WB; tested species: mouse

Mitofusin 2 Sustains the Axonal Mitochondrial Network to Support Presynaptic Ca2+ Homeostasis and the Synaptic Vesicle Cycle in Rat Hippocampal Axons.
Vevea JD, Chapman ER
The Journal of neuroscience : the official journal of the Society for Neuroscience (2023) 4319: 3421-3438. 103 002 WB; tested species: rat

Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
Xie YX, Naseri NN, Fels J, Kharel P, Na Y, Lane D, Burré J, Sharma M
Nature communications (2022) 131: 4918. 103 002 WB; tested species: mouse

Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons.
De Pace R, Britt DJ, Mercurio J, Foster AM, Djavaherian L, Hoffmann V, Abebe D, Bonifacino JS
Cell reports (2020) 3111: 107775. 103 002 WB; tested species: mouse

Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts.
Raja MK, Preobraschenski J, Del Olmo-Cabrera S, Martinez-Turrillas R, Jahn R, Perez-Otano I, Wesseling JF
eLife (2019) 8: . 103 002 WB; KO verified; tested species: mouse

SV31 is a Zn2+-binding synaptic vesicle protein.
Barth J, Zimmermann H, Volknandt W
Journal of neurochemistry (2011) 1184: 558-70. 103 002 WB

Synaptic and vesicular coexistence of VGLUT and VGAT in selected excitatory and inhibitory synapses.
Zander JF, Münster-Wandowski A, Brunk I, Pahner I, Gómez-Lira G, Heinemann U, Gutiérrez R, Laube G, Ahnert-Hilger G
The Journal of neuroscience : the official journal of the Society for Neuroscience (2010) 3022: 7634-45. 103 002 WB; tested species: rat

Cat. No.: 103 002

Amount: 200 µl

Price: $360.00

ICC

IHC

IHC-P

Background

Protocols

Synaptogyrin1 antibody - 103 002 K.O.